Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 11:12 p.m.

In MLB action on Sunday, the San Diego Padres take on the Miami Marlins.

We've got you covered, in terms of the vital info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Marlins Game Info

• San Diego Padres (85-69) vs. Miami Marlins (76-78)
• Date: Sunday, September 20, 2026
• Time: 4:10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Marlins.TV

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-156) | MIA: (+132)
• Spread: SD: -1.5 (+142) | MIA: +1.5 (-172)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 8-6, 4.58 ERA vs Sandy Alcantara (Marlins) - 13-10, 3.84 ERA

The probable starters are Walker Buehler (8-6) for the Padres and Sandy Alcantara (13-10) for the Marlins. Buehler and his team have a record of 22-8-0 against the spread when he starts. Buehler's team has a record of 8-4 this season when he starts and they are the favorite on the moneyline. When Alcantara starts, the Marlins are 17-15-0 against the spread. The Marlins have a 6-10 record in Alcantara's 16 starts this season when they were the moneyline underdog.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (51.2%)

Padres vs Marlins Moneyline

• Looking at the moneyline for Marlins-Padres, Miami is the underdog at +132, and San Diego is -156 playing at home.

Padres vs Marlins Spread

• The Marlins are at +1.5 on the runline against the Padres. The Marlins are -172 to cover the spread, and the Padres are +142.

Padres vs Marlins Over/Under

• An over/under of 7.5 has been set for Padres-Marlins on Sept. 20, with the over being -110 and the under -110.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have won in 46, or 60.5%, of the 76 contests they have been named as odds-on favorites in this year.
• San Diego has a record of 18-8 when favored by -156 or more this year.
• The Padres and their opponents have gone over the total this season in 72 of their 154 opportunities.
• The Padres have an against the spread record of 89-65-0 in 154 games with a line this season.
• The Marlins have a 35-51 record in games they were listed as the moneyline underdog (winning 40.7% of those games).
• Miami has a record of 5-16 when playing as a moneyline underdog with odds of +132 or longer (23.8%).
• The Marlins have had an over/under set by bookmakers 152 times, and have combined with opponents to go over the total in 77 of those games (77-73-2).
• The Marlins have a 78-74-0 record against the spread this season (covering 51.3% of the time).

Padres Player Leaders

• Fernando Tatis Jr. has 171 hits and an OBP of .355 to go with a slugging percentage of .461. All three of those stats are best among San Diego hitters this season. He has a .285 batting average, as well.
• Among qualified batters in MLB, he is 16th in batting average, 38th in on-base percentage, and 36th in slugging.
• Tatis hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .182 with a double, two home runs, two walks and four RBIs.
• Jackson Merrill has 25 doubles, five triples, 26 home runs and 39 walks. He's batting .256 and slugging .448 with an on-base percentage of .304.
• Among qualified batters, he ranks 69th in batting average, 113th in on-base percentage and 48th in slugging percentage.
• Merrill enters this game looking to extend his nine-game hit streak. In his last 10 games he is hitting .442 with two doubles, two triples, four home runs, a walk and 14 RBIs.
• Manny Machado has 122 hits this season and has a slash line of .219/.308/.409.
• Xander Bogaerts is batting .228 with a .326 OBP and 56 RBI for San Diego this season.
• Bogaerts heads into this game on a two-game hitting streak. During his last five outings he is hitting .389 with two doubles, a triple, a home run, three walks and two RBIs.

Marlins Player Leaders

• Otto Lopez has a .441 slugging percentage, which leads the Marlins. He's batting .307 with an on-base percentage of .349.
• Including all the qualifying hitters in the big leagues, he is fourth in batting average, 44th in on-base percentage and 55th in slugging percentage.
• Xavier Edwards leads his team with a .361 on-base percentage. He has a batting average of .282 while slugging .373.
• He is 20th in batting average, 28th in on-base percentage and 111th in slugging percentage in the big leagues.
• Javier Sanoja has 31 doubles, five triples, nine home runs and 25 walks while hitting .294.
• Jakob Marsee has 19 doubles, six triples, 11 home runs and 75 walks while hitting .228.

Padres vs Marlins Head to Head

• 9/18/2026: 8-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 7/26/2026: 5-3 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/25/2026: 7-2 SD (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/24/2026: 4-2 SD (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/23/2025: 3-2 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)

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