Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 4:11 p.m.

On Sunday in MLB, the San Diego Padres are up against the Miami Marlins.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Marlins Game Info

• San Diego Padres (86-69) vs. Miami Marlins (76-79)
• Date: Sunday, September 20, 2026
• Time: 4:10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Marlins.TV

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-156) | MIA: (+132)
• Spread: SD: -1.5 (+142) | MIA: +1.5 (-172)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 8-6, 4.58 ERA vs Sandy Alcantara (Marlins) - 13-10, 3.84 ERA

The Padres will give the ball to Walker Buehler (8-6, 4.58 ERA), who is eyeing win No. 9 on the season, and the Marlins will turn to Sandy Alcantara (13-10, 3.84 ERA). Buehler and his team are 22-8-0 ATS this season when he starts. Buehler's team has won 66.7% of his starts when they are favored on the moneyline (8-4). The Marlins have gone 17-15-0 against the spread when Alcantara starts. The Marlins are 6-10 in Alcantara's 16 starts this season that they were the moneyline underdog.

Padres vs Marlins Moneyline

• San Diego is a -156 favorite on the moneyline, while Miami is a +132 underdog on the road.

Padres vs Marlins Spread

• The Padres are 1.5-run home favorites on the runline against the Marlins. The Padres are +142 to cover, and the Marlins are -172.

Padres vs Marlins Over/Under

• The over/under for Padres-Marlins on Sept. 20 is 7.5. The over is -110, and the under is -110.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have been victorious in 47, or 61%, of the 77 contests they have been chosen as favorites in this season.
• San Diego has a record of 19-8 in contests when sportsbooks favor them by -156 or more on the moneyline.
• The Padres and their opponents have gone over the total this season in 73 of their 155 opportunities.
• The Padres are 89-66-0 against the spread in their 155 games that had a posted line this season.
• The Marlins have been the moneyline underdog 87 total times this season. They've finished 35-52 in those games.
• Miami has a 5-16 record (winning just 23.8% of its games) when playing as a moneyline underdog of +132 or longer.
• The Marlins have played in 153 games with an over/under set, and have combined with opponents to go over the total 78 times (78-73-2).
• The Marlins have gone 79-74-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.355), slugging percentage (.464) and total hits (172) this season. He has a .285 batting average.
• Among all qualifying hitters in MLB, he ranks 16th in batting average, 39th in on-base percentage, and 35th in slugging.
• Tatis will look for his fourth straight game with a hit in this contest. In his last five games he is hitting .190 with a double, two home runs, two walks and three RBIs.
• Jackson Merrill is hitting .255 with 25 doubles, five triples, 26 home runs and 40 walks, while slugging .447 with an on-base percentage of .305.
• He ranks 69th in batting average, 111th in on-base percentage and 49th in slugging in MLB.
• Merrill takes a 10-game streak with at least one hit into this one. In his last 10 games he is hitting .455 with two doubles, two triples, four home runs, two walks and 13 RBIs.
• Manny Machado is batting .220 with a .409 slugging percentage and 84 RBI this year.
• Ty France is batting .304 with a .369 OBP and 70 RBI for San Diego this season.
• France brings a four-game hitting streak into this game. In his last five games he is hitting .429 with three doubles, a home run and six RBIs.

Marlins Player Leaders

• Otto Lopez has a .444 slugging percentage, which paces the Marlins. He's batting .307 with an on-base percentage of .350.
• Including all the qualifying hitters in the majors, his batting average ranks fourth, his on-base percentage ranks 42nd, and he is 51st in slugging.
• Lopez hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .238 with a double, a home run, four walks and two RBIs.
• Xavier Edwards leads his team with a .360 OBP. He has a batting average of .280 while slugging .371.
• His batting average ranks 23rd among all qualified players, his on-base percentage is 29th, and he is 114th in slugging.
• Javier Sanoja is hitting .291 with 31 doubles, five triples, nine home runs and 26 walks.
• Jakob Marsee is batting .232 with 19 doubles, six triples, 11 home runs and 76 walks.

Padres vs Marlins Head to Head

• 9/19/2026: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/18/2026: 8-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 7/26/2026: 5-3 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/25/2026: 7-2 SD (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/24/2026: 4-2 SD (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/23/2025: 3-2 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)

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