Odds updated as of 12:12 PM

MLB action on Wednesday includes the Baltimore Orioles facing the St. Louis Cardinals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Orioles vs Cardinals Game Info

• Baltimore Orioles (29-16) vs. St. Louis Cardinals (21-26)
• Date: Wednesday, May 22, 2024
• Time: 12:15 PM ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: MASN2

Orioles vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-126) | STL: (+108)
• Spread: BAL: -1.5 (+125) | STL: +1.5 (-150)
• Total: 9 -- Over: (-110) | Under: (-110)

Orioles vs Cardinals Probable Starting Pitchers

Probable Pitchers: Kyle Bradish (Orioles) - 0-0, 2.63 ERA vs Lance Lynn (Cardinals) - 1-2, 4.17 ERA

The Orioles will call on Kyle Bradish versus the Cardinals and Lance Lynn (1-2). Bradish's team is 1-2-0 against the spread in his starts this season. Bradish's team has won each of the three games he's started as the moneyline favorite. The Cardinals have a 4-5-0 ATS record in Lynn's nine starts with a set spread. The Cardinals have been the moneyline underdog in four of Lynn's starts this season, and they went 1-3 in those matchups.

Orioles vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Orioles win (58.8%)

Orioles vs Cardinals Moneyline

• Baltimore is a -126 favorite on the moneyline, while St. Louis is a +108 underdog at home.

Orioles vs Cardinals Spread

• The Cardinals are +1.5 on the run line against the Orioles. The Cardinals are -150 to cover, and the Orioles are +125.

Orioles vs Cardinals Over/Under

• A total of 9 runs has been set for the Orioles-Cardinals contest on May 22, with the over available at -110 and the under at -110.

Bet on Baltimore Orioles vs. St. Louis Cardinals on FanDuel today!

Orioles vs Cardinals Betting Trends

• The Orioles have been chosen as favorites in 34 games this year and have walked away with the win 21 times (61.8%) in those games.
• This season Baltimore has come away with a win 17 times in 29 chances when named as a favorite of at least -126 on the moneyline.
• The Orioles' games have gone over the total in 23 of their 42 opportunities.
• The Orioles are 22-20-0 against the spread in their 42 games that had a posted line this season.
• The Cardinals have won nine of the 22 games they were listed as the moneyline underdog this season (40.9%).
• In games it has played as a moneyline underdog with odds of +108 or longer, St. Louis has a 4-9 record (winning only 30.8% of its games).
• The Cardinals have combined with opponents to hit the over on the total 22 times this season for a 22-23-2 record against the over/under.
• The Cardinals have a 22-25-0 record against the spread this season.

Orioles Player Leaders

• Gunnar Henderson has 48 hits, which leads Baltimore hitters this season, while batting .271 with 24 extra-base hits. He has an on-base percentage of .351 and a slugging percentage of .610.
• Among qualified hitters in baseball, his batting average ranks 42nd, his on-base percentage ranks 36th, and he is fourth in slugging.
• Henderson hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .333 with a triple, four home runs, four walks and seven RBI.
• Adley Rutschman leads Baltimore in slugging percentage (.492) thanks to 16 extra-base hits. He's batting .304 with an on-base percentage of .342.
• His batting average ranks 16th among qualified players, his on-base percentage 48th, and his slugging percentage 27th.
• Jordan Westburg has collected 47 base hits, an OBP of .345 and a slugging percentage of .519 this season.
• Westburg takes a three-game hitting streak into this matchup. In his last five games he is hitting .263 with a triple, a home run, a walk and two RBI.
• Anthony Santander is batting .205 with a .283 OBP and 25 RBI for Baltimore this season.

Cardinals Player Leaders

• Brendan Donovan is batting .232 with 11 doubles, a triple, four home runs and 17 walks. He's slugging .370 with an on-base percentage of .311.
• Including all qualified hitters in the big leagues, he is 107th in batting average, 101st in on-base percentage and 117th in slugging percentage.
• Donovan enters this game on an eight-game hitting streak. In his last 10 games he is batting .262 with three doubles, six walks and two RBI.
• Nolan Arenado's .371 slugging percentage leads his team. He has a batting average of .270 with an on-base percentage of .325.
• Including all qualified hitters, he ranks 44th in batting average, 75th in on-base percentage and 116th in slugging percentage.
• Lars Nootbaar is batting .213 with seven doubles, five home runs and 22 walks.
• Masyn Winn's 38 hits and .345 on-base percentage both lead his team.

Orioles vs Cardinals Head to Head

• 5/20/2024: 6-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/12/2023: 5-2 STL (Favorite: Orioles, Spread: -1.5, Total: 11, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/11/2023: 11-5 BAL (Favorite: Orioles, Spread: -1.5, Total: 10, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/11/2022: 10-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 5/10/2022: 5-3 BAL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/13/2023: 1-0 STL (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -188, Underdog Moneyline: +158)

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