Ole Miss vs Charlotte Prediction, Odds, Picks, Best Bets for Week 2 2026

Saturday's slate in college football includes a matchup between the Ole Miss Rebels and the Charlotte 49ers.

We've got you covered, in terms of the vital info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Ole Miss vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ole Miss: (N/A) | Charlotte: (N/A)
• Spread: Ole Miss: -45.5 (-104) | Charlotte: +45.5 (-118)
• Total: 59.5 -- Over: (-105) | Under: (-115)

Ole Miss vs Charlotte Betting Trends

• Ole Miss has no wins against the spread this year.
• One of Ole Miss' one games this season has hit the over.
• Charlotte has not won a game against the spread this year.
• All one Charlotte games have hit the over this season.

Ole Miss vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (99.5%)

Ole Miss vs Charlotte Point Spread

Ole Miss is favored by 45.5 points against Charlotte. Ole Miss is -104 to cover the spread, while Charlotte is -118.

Ole Miss vs Charlotte Over/Under

The over/under for the Ole Miss versus Charlotte matchup on Sept. 12 has been set at 59.5, with -105 odds on the over and -115 odds on the under.

Ole Miss vs. Charlotte Points Insights

• The Rebels had an average implied point total of 35.9 last season, which is 17.1 points lower than their implied total in Saturday's game (53).
• The 36.1-point average implied total last season for the 49ers is 29.1 more points than the team's 7-point implied total in this matchup.

Ole Miss vs. Charlotte Game Info

• Game day: Saturday, September 12, 2026
• Game time: 7:45 p.m. ET
• TV channel: ESPN2
• Location: Oxford, Mississippi
• Stadium: Vaught-Hemingway Stadium

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Check out even more in-depth Ole Miss vs. Charlotte analysis on FanDuel Research.