Ole Miss vs Charlotte Prediction, Odds, Picks, Best Bets for Week 2 2026

College football's Saturday schedule includes the Ole Miss Rebels taking on the Charlotte 49ers.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Ole Miss vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ole Miss: (N/A) | Charlotte: (N/A)
• Spread: Ole Miss: -47.5 (-106) | Charlotte: +47.5 (-114)
• Total: 61.5 -- Over: (-108) | Under: (-112)

Ole Miss vs Charlotte Betting Trends

• Ole Miss hasn't won a game against the spread this year.
• All one of Ole Miss' games have hit the over this season.
• Charlotte has no wins against the spread this season.
• Every Charlotte game has gone over the point total this year.

Ole Miss vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (99.5%)

Ole Miss vs Charlotte Point Spread

Charlotte is the underdog by 47.5 points against Ole Miss. Charlotte is -106 to cover the spread, and Ole Miss is -114.

Ole Miss vs Charlotte Over/Under

Ole Miss versus Charlotte, on Sept. 12, has an over/under of 61.5, with the over being -108 and the under -112.

Ole Miss vs. Charlotte Points Insights

• The Rebels had an average implied point total of 35.9 last season, which is 19.1 points lower than their implied total in Saturday's game (55).
• The 36.1-point average implied total last season for the 49ers is 29.1 more points than the team's 7-point implied total in this matchup.

Ole Miss vs. Charlotte Game Info

• Game day: Saturday, September 12, 2026
• Game time: 7:45 p.m. ET
• TV channel: ESPN2
• Location: Oxford, Mississippi
• Stadium: Vaught-Hemingway Stadium

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Check out even more in-depth Ole Miss vs. Charlotte analysis on FanDuel Research.