Old Dominion vs East Carolina Prediction, Odds, Picks, Best Bets for Week 3 2026

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The Old Dominion Monarchs are among the college football squads playing on Saturday, versus the East Carolina Pirates.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Old Dominion vs East Carolina Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Old Dominion: (-140) | East Carolina: (+116)
Spread: Old Dominion: -2.5 (-122) | East Carolina: +2.5 (100)
Total: 49.5 -- Over: (-105) | Under: (-115)

Old Dominion is winless against the spread this season.
Old Dominion has no wins ATS (0-1) as a 2.5-point favorite or greater this year.
One of Old Dominion's two games this season has hit the over.
East Carolina has not won a game against the spread this year.
East Carolina doesn't have a win ATS (0-1) as a 2.5-point underdog or greater this season.
East Carolina has had one game (of two) hit the over this season.

All college football win probability predictions and picks are according to numberFire.
Prediction: Monarchs win (66.9%)

East Carolina is listed as an underdog by 2.5 points (+100 odds), and Old Dominion, the favorite, is -122 to cover.

The Old Dominion-East Carolina matchup on Sept. 19 has been given an over/under of 49.5 points. The over is -105 and the under is -115.

Old Dominion is a -140 favorite on the moneyline, while East Carolina is a +116 underdog.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Old Dominion	26.0	91	27.0	90	50.0	2
East Carolina	17.0	123	37.5	123	54.0	2

Check out even more in-depth Old Dominion vs. East Carolina analysis on FanDuel Research.

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