Old Dominion vs East Carolina Prediction, Odds, Picks, Best Bets for Week 3 2026

In college football action on Saturday, the Old Dominion Monarchs face the East Carolina Pirates.

We've got you covered, in terms of the most important information regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Old Dominion vs East Carolina Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Old Dominion: (-140) | East Carolina: (+116)
• Spread: Old Dominion: -2.5 (-122) | East Carolina: +2.5 (100)
• Total: 49.5 -- Over: (-105) | Under: (-115)

Old Dominion vs East Carolina Betting Trends

• Old Dominion has no wins against the spread this season.
• Old Dominion has yet to win ATS (0-1) when playing as at least 2.5-point favorites this season.
• One of two Old Dominion games have hit the over this season.
• East Carolina has no wins against the spread this season.
• East Carolina doesn't have a win ATS (0-1) as a 2.5-point underdog or greater this year.
• One of East Carolina's two games has hit the over.

Old Dominion vs East Carolina Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Monarchs win (62.5%)

Old Dominion vs East Carolina Point Spread

Old Dominion is favored by 2.5 points over East Carolina. Old Dominion is -122 to cover the spread, with East Carolina being +100.

Old Dominion vs East Carolina Over/Under

Old Dominion versus East Carolina on Sept. 19 has an over/under of 49.5 points, with the over -105 and the under -115.

Old Dominion vs East Carolina Moneyline

Old Dominion is the favorite, -140 on the moneyline, while East Carolina is a +116 underdog.

Old Dominion vs. East Carolina Points Insights

Old Dominion vs. East Carolina Game Info

• Game day: Saturday, September 19, 2026
• Game time: 6 p.m. ET
• TV channel: ESPN+
• Location: Norfolk, Virginia
• Stadium: Kornblau Field at S.B. Ballard Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Old Dominion vs. East Carolina analysis on FanDuel Research.