Ohio State vs Northwestern Prediction, Odds, Picks, Best Bets for Week 11 2026

The college football schedule on Saturday includes the Ohio State Buckeyes taking on the Northwestern Wildcats.

We've got you covered, in terms of the most important information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Ohio State vs Northwestern Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio State: (-629) | Northwestern: (+460)
• Spread: Ohio State: -13.5 (-120) | Northwestern: +13.5 (100)
• Total: 44.5 -- Over: (-110) | Under: (-110)

Ohio State vs Northwestern Betting Trends

• Against the spread, Ohio State is 5-4-0 this season.
• As 13.5-point favorites or more, Ohio State is 3-2 against the spread.
• There have been five Ohio State games (of nine) that went over the total this season.
• Against the spread, Northwestern is 5-4-0 this year.
• Northwestern is unbeaten ATS (1-0) as a 13.5-point underdog or more this year.
• This year, five of Northwestern's nine games have hit the over.

Ohio State vs Northwestern Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Buckeyes win (84.5%)

Ohio State vs Northwestern Point Spread

Northwestern is a 13.5-point underdog against Ohio State. Northwestern is +100 to cover the spread, and Ohio State is -120.

Ohio State vs Northwestern Over/Under

The Ohio State-Northwestern matchup on Nov. 14 has been given an over/under of 44.5 points. The over is -110 and the under is -110.

Ohio State vs Northwestern Moneyline

Looking at the moneyline for Ohio State-Northwestern, Ohio State is the favorite at -629, and Northwestern is +460.

Ohio State vs. Northwestern Points Insights

Ohio State vs. Northwestern Game Info

• Game day: Saturday, November 14, 2026
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Columbus, Ohio
• Stadium: Ohio Stadium

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Check out even more in-depth Ohio State vs. Northwestern analysis on FanDuel Research.