Notre Dame vs Wisconsin Prediction, Odds, Picks, Best Bets for Week 1 2026

NCAA football action on Sunday includes the Notre Dame Fighting Irish playing the Wisconsin Badgers.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding today's NCAA football betting odds.

Notre Dame vs Wisconsin Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Notre Dame: (-2222) | Wisconsin: (+1100)
• Spread: Notre Dame: -21.5 (-102) | Wisconsin: +21.5 (-120)
• Total: 46.5 -- Over: (-110) | Under: (-110)

Notre Dame vs Wisconsin Betting Trends

• Against the spread, Notre Dame went 6-6-0 last year.
• As 21.5-point or greater favorites last season, Notre Dame went 4-3.
• Out of 12 Notre Dame games last season, seven went over the total.
• Against the spread, Wisconsin was 6-6-0 last year.
• As 21.5-point underdogs or more, Wisconsin had two wins ATS (2-1) last season.
• Two Wisconsin games (of 12) hit the over last season.

Notre Dame vs Wisconsin Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Fighting Irish win (93.8%)

Notre Dame vs Wisconsin Point Spread

Notre Dame is a 21.5-point favorite against Wisconsin. Notre Dame is -102 to cover the spread, and Wisconsin is -120.

Notre Dame vs Wisconsin Over/Under

Notre Dame versus Wisconsin, on Sept. 6, has an over/under of 46.5, with the over being -110 and the under -110.

Notre Dame vs Wisconsin Moneyline

The Notre Dame vs Wisconsin moneyline has Notre Dame as a -2222 favorite, while Wisconsin is a +1100 underdog.

Notre Dame vs. Wisconsin Points Insights

• The Fighting Irish's average implied point total last season was 3.7 more points than their implied total in Sunday's game (37.7 implied points on average compared to 34 implied points in this game).
• The Badgers' average implied point total last season (30.1 points) is 17.1 points higher than their implied total in this matchup (13 points).

Notre Dame vs. Wisconsin Game Info

• Game day: Sunday, September 6, 2026
• Game time: 7:30 p.m. ET
• TV channel: NBC/Peacock
• Location: Green Bay, Wisconsin
• Stadium: Lambeau Field

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