Notre Dame vs Wisconsin Prediction, Odds, Picks, Best Bets for Week 1 2026

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Sunday's slate in college football includes a matchup between the Notre Dame Fighting Irish and the Wisconsin Badgers.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Notre Dame vs Wisconsin Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Notre Dame: (-1786) | Wisconsin: (+980)
Spread: Notre Dame: -20.5 (-110) | Wisconsin: +20.5 (-110)
Total: 46.5 -- Over: (-110) | Under: (-110)

Notre Dame beat the spread six times in 12 games last year.
Notre Dame had an ATS record of 4-3 as favorites of 20.5 points or more last season.
Out of 12 Notre Dame games last season, seven hit the over.
Wisconsin had six wins in 12 games against the spread last season.
As 20.5-point underdogs or more, Wisconsin had two wins ATS (2-1) last season.
Two of Wisconsin's 12 games last season went over the point total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Fighting Irish win (93.6%)

Notre Dame is favored by 20.5 points against Wisconsin. Notre Dame is -110 to cover the spread, while Wisconsin is -110.

Notre Dame versus Wisconsin, on Sept. 6, has an over/under of 46.5, with the over being -110 and the under -110.

Notre Dame is a -1786 favorite on the moneyline, while Wisconsin is a +980 underdog.

The Fighting Irish had an average implied point total of 37.7 last season, which is 3.7 points higher than their implied total in Sunday's game (34).
The Badgers' average implied point total last season (30.1 points) is 17.1 points higher than their implied total in this matchup (13 points).

Check out even more in-depth Notre Dame vs. Wisconsin analysis on FanDuel Research.

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