NFL Games This Week: Odds, Predictions, Picks, TV Info & More – Week 16

The Week 16 NFL schedule features top teams in action. Among those contests is the Baltimore Ravens squaring off against the San Francisco 49ers.
To pick up an edge before Week 16 in the NFL, check out our betting preview below.
Rams vs. Saints
Kyren Williams will lead the Los Angeles Rams into their game versus the New Orleans Saints at SoFi Stadium on Thursday at 8:15 PM ET.
- Matchup: New Orleans Saints at Los Angeles Rams
- Projected Favorite: Rams (67.20% win probability)
- Spread: Los Angeles (-4.5)
- Time: 8:15 PM ET
- Channel: Amazon Prime Video
Bet on Los Angeles vs. New Orleans with FanDuel Sportsbook.
Steelers vs. Bengals
One of the top running backs in football will be featured when Joe Mixon and the Cincinnati Bengals visit the Pittsburgh Steelers on Saturday, December 23, 2023.
- Matchup: Cincinnati Bengals at Pittsburgh Steelers
- Projected Favorite: Bengals (57.23% win probability)
- Spread: Cincinnati (-3)
- Time: 4:30 PM ET
- Channel: NBC
Bet on Pittsburgh vs. Cincinnati with FanDuel Sportsbook.
Chargers vs. Bills
Star running back James Cook and the Buffalo Bills play the Los Angeles Chargers on Saturday at 8:00 PM ET at SoFi Stadium.
- Matchup: Buffalo Bills at Los Angeles Chargers
- Spread: Buffalo (-12.5)
- Time: 8:00 PM ET
- Channel: Peacock
Bet on Los Angeles vs. Buffalo with FanDuel Sportsbook.
Titans vs. Seahawks
Derrick Henry will lead the Tennessee Titans into their matchup against the Seattle Seahawks at Nissan Stadium, on Sunday at 1:00 PM ET.
- Matchup: Seattle Seahawks at Tennessee Titans
- Projected Favorite: Titans (50.94% win probability)
- Spread: Seattle (-3)
- Time: 1:00 PM ET
- Channel: CBS
Bet on Tennessee vs. Seattle with FanDuel Sportsbook.
Vikings vs. Lions
At U.S. Bank Stadium on Sunday, Amon-Ra St. Brown and the Detroit Lions play T.J. Hockenson and the Minnesota Vikings in a battle featuring two excellent pass-catchers, starting at 1:00 PM ET.
- Matchup: Detroit Lions at Minnesota Vikings
- Projected Favorite: Lions (61.84% win probability)
- Spread: Detroit (-3)
- Time: 1:00 PM ET
- Channel: FOX
Bet on Minnesota vs. Detroit with FanDuel Sportsbook.
Texans vs. Browns
The Houston Texans are in action on Sunday at 1:00 PM ET at NRG Stadium against the Cleveland Browns.
- Matchup: Cleveland Browns at Houston Texans
- Projected Favorite: Texans (56.93% win probability)
- Spread: Cleveland (-3)
- Time: 1:00 PM ET
- Channel: CBS
Bet on Houston vs. Cleveland with FanDuel Sportsbook.
Falcons vs. Colts
At 1:00 PM ET on Sunday, the Indianapolis Colts play at the Atlanta Falcons.
- Matchup: Indianapolis Colts at Atlanta Falcons
- Projected Favorite: Falcons (53.75% win probability)
- Spread: Atlanta (-3)
- Time: 1:00 PM ET
- Channel: FOX
Bet on Atlanta vs. Indianapolis with FanDuel Sportsbook.
Panthers vs. Packers
The Green Bay Packers will visit the Carolina Panthers on Sunday at 1:00 PM ET.
- Matchup: Green Bay Packers at Carolina Panthers
- Projected Favorite: Packers (62.92% win probability)
- Spread: Green Bay (-3.5)
- Time: 1:00 PM ET
- Channel: FOX
Bet on Carolina vs. Green Bay with FanDuel Sportsbook.
Jets vs. Commanders
MetLife Stadium is the venue where the New York Jets will match up against the Washington Commanders on Sunday, December 24, 2023.
- Matchup: Washington Commanders at New York Jets
- Projected Favorite: Jets (52.76% win probability)
- Spread: New York (-3)
- Time: 1:00 PM ET
- Channel: CBS
Bet on New York vs. Washington with FanDuel Sportsbook.
Buccaneers vs. Jaguars
Two excellent running backs will be on display when Travis Etienne and the Jacksonville Jaguars visit Rachaad White and the Tampa Bay Buccaneers on Sunday, December 24, 2023.
- Matchup: Jacksonville Jaguars at Tampa Bay Buccaneers
- Projected Favorite: Buccaneers (54.60% win probability)
- Spread: Jacksonville (-1.5)
- Time: 4:05 PM ET
- Channel: CBS
Bet on Tampa Bay vs. Jacksonville with FanDuel Sportsbook.
Bears vs. Cardinals
D.J. Moore will lead the Chicago Bears into their battle versus the Arizona Cardinals at Soldier Field on Sunday at 4:25 PM ET.
- Matchup: Arizona Cardinals at Chicago Bears
- Projected Favorite: Bears (63.87% win probability)
- Spread: Chicago (-3.5)
- Time: 4:25 PM ET
- Channel: FOX
Bet on Chicago vs. Arizona with FanDuel Sportsbook.
Dolphins vs. Cowboys
At Hard Rock Stadium on Sunday, Tyreek Hill and the Miami Dolphins face Dak Prescott and the Dallas Cowboys in a matchup between a pair of the biggest stars in football, beginning at 4:25 PM ET.
- Matchup: Dallas Cowboys at Miami Dolphins
- Projected Favorite: Dolphins (64.08% win probability)
- Spread: Miami (-1.5)
- Time: 4:25 PM ET
- Channel: FOX
Bet on Miami vs. Dallas with FanDuel Sportsbook.
Broncos vs. Patriots
Empower Field at Mile High is the venue where the Denver Broncos will match up against the New England Patriots on Sunday, December 24, 2023.
- Matchup: New England Patriots at Denver Broncos
- Projected Favorite: Broncos (75.64% win probability)
- Spread: Denver (-7.5)
- Time: 8:15 PM ET
- Channel: NFL Network
Bet on Denver vs. New England with FanDuel Sportsbook.
Chiefs vs. Raiders
Travis Kelce will lead the Kansas City Chiefs into their game versus the Las Vegas Raiders at GEHA Field at Arrowhead Stadium on Monday at 1:00 PM ET.
- Matchup: Las Vegas Raiders at Kansas City Chiefs
- Projected Favorite: Chiefs (69.95% win probability)
- Spread: Kansas City (-10.5)
- Time: 1:00 PM ET
- Channel: CBS
Bet on Kansas City vs. Las Vegas with FanDuel Sportsbook.
Eagles vs. Giants
A.J. Brown and the Philadelphia Eagles face the New York Giants on Monday at 4:30 PM ET, at Lincoln Financial Field.
- Matchup: New York Giants at Philadelphia Eagles
- Projected Favorite: Eagles (83.46% win probability)
- Spread: Philadelphia (-13.5)
- Time: 4:30 PM ET
- Channel: FOX
Bet on Philadelphia vs. New York with FanDuel Sportsbook.
49ers vs. Ravens
At Levi's Stadium on Monday, Christian McCaffrey and the San Francisco 49ers face Lamar Jackson and the Baltimore Ravens in a matchup between a pair of the brightest stars in football on offense, starting at 8:15 PM ET.
- Matchup: Baltimore Ravens at San Francisco 49ers
- Projected Favorite: 49ers (65.93% win probability)
- Spread: San Francisco (-6.5)
- Time: 8:15 PM ET
- Channel: ABC
Bet on San Francisco vs. Baltimore with FanDuel Sportsbook.
Matchup favorites and win projections are provided by numberFire.
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