Nebraska vs Ohio Prediction, Odds, Picks, Best Bets for Week 1 2026

The Nebraska Cornhuskers versus the Ohio Bobcats is on the college football schedule for Saturday.

We've got you covered, in terms of the vital information regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Nebraska vs Ohio Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Nebraska: (-4545) | Ohio: (+1600)
• Spread: Nebraska: -23.5 (-122) | Ohio: +23.5 (100)
• Total: 46.5 -- Over: (-105) | Under: (-115)

Nebraska vs Ohio Betting Trends

• Nebraska was 4-8-1 against the spread last year.
• Nebraska covered every time (2-0) as a 23.5-point or higher favorite last year.
• In 13 Nebraska games last season, 10 went over the total.
• Ohio posted a 7-6-0 record against the spread last year.
• Ohio covered every time (1-0) as underdogs of 23.5 points or more last year.
• Last year, six of Ohio's 13 games hit the over.

Nebraska vs Ohio Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cornhuskers win (88.2%)

Nebraska vs Ohio Point Spread

Ohio is an underdog by 23.5 points against Nebraska. Ohio is +100 to cover the spread, and Nebraska is -122.

Nebraska vs Ohio Over/Under

A combined point total of 46.5 has been set for Nebraska-Ohio on Sept. 5, with the over at -105 and the under at -115.

Nebraska vs Ohio Moneyline

The Nebraska vs Ohio moneyline has Nebraska as a -4545 favorite, while Ohio is a +1600 underdog.

Nebraska vs. Ohio Points Insights

• The average implied total for the Cornhuskers last season was 30.3 points, 4.7 fewer points than their implied total of 35 points in Saturday's game.
• The average implied point total last season for the Bobcats (33.0) is 21.0 more points than the team's implied total in this matchup (12).

Nebraska vs. Ohio Game Info

• Game day: Saturday, September 5, 2026
• Game time: 12 p.m. ET
• TV channel: Fox Sports 1
• Location: Lincoln, Nebraska
• Stadium: Memorial Stadium (Lincoln, NE)

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Check out even more in-depth Nebraska vs. Ohio analysis on FanDuel Research.