Tuesday’s MLB Strikeout Props - Sept. 22

Will Logan Gilbert strike out more than 5.5 batters? Can Brandon Williamson record more than 2.5 strikeouts? See their odds and more strikeout prop odds for all pitchers in MLB play on Sept. 22, in the article below.

Today's MLB Strikeout Props

Cincinnati Reds at Atlanta Braves

• JR Ritchie (Braves): Over/Under 4.5 Ks (Over -122, Under -104) | 2026 Stats: 3.9 strikeouts per game in 15 appearances
• Brandon Williamson (Reds): Over/Under 2.5 Ks (Over -146, Under +114) | 2026 Stats: 3.1 strikeouts per game in 10 appearances

Tampa Bay Rays at New York Yankees

• Carlos Rodon (Yankees): Over/Under 4.5 Ks (Over -154, Under +120) | 2026 Stats: 5.5 strikeouts per game in 15 appearances

Tampa Bay Rays at New York Yankees

• Carlos Rodon (Yankees): Over/Under 4.5 Ks (Over -154, Under +120) | 2026 Stats: 5.5 strikeouts per game in 15 appearances

New York Mets at Texas Rangers

• Sean Manaea (Mets): Over/Under 4.5 Ks (Over -120, Under -106) | 2026 Stats: 4.3 strikeouts per game in 31 appearances
• MacKenzie Gore (Rangers): Over/Under 4.5 Ks (Over +126, Under -162) | 2026 Stats: 5.4 strikeouts per game in 32 appearances

Houston Astros at Seattle Mariners

• Logan Gilbert (Mariners): Over/Under 5.5 Ks (Over -156, Under +122) | 2026 Stats: 6.5 strikeouts per game in 30 appearances
• Cristian Javier (Astros): Over/Under 4.5 Ks (Over +110, Under -140) | 2026 Stats: 3.6 strikeouts per game in 16 appearances

Cleveland Guardians at Boston Red Sox

• Payton Tolle (Red Sox): Over/Under 5.5 Ks (Over -122, Under -104) | 2026 Stats: 6.6 strikeouts per game in 25 appearances
• Parker Messick (Guardians): Over/Under 5.5 Ks (Over -142, Under +112) | 2026 Stats: 6.2 strikeouts per game in 30 appearances

Milwaukee Brewers at Philadelphia Phillies

• Dustin May (Brewers): Over/Under 3.5 Ks (Over -115, Under -111) | 2026 Stats: 4.7 strikeouts per game in 29 appearances

Chicago White Sox at Kansas City Royals

• Daniel Lynch (Royals): Over/Under 3.5 Ks (Over +124, Under -158) | 2026 Stats: 1 strikeouts per game in 54 appearances
• Anthony Kay (White Sox): Over/Under 3.5 Ks (Over -146, Under +114) | 2026 Stats: 3.9 strikeouts per game in 31 appearances