Friday’s MLB Odds, Betting Lines and Predictions - Sept. 25

Friday's MLB slate features the Chicago Cubs squaring off against the Boston Red Sox at Fenway Park. We have predictions for every game on the schedule, so check them out below.

Today's MLB Odds and Predictions

Chicago Cubs at Boston Red Sox

Game Info

• When: 1:05 p.m. ET
• Where: Fenway Park
• TV Channel: NESN and MARQ
• Probable Pitchers: vs. David Peterson
• Records: Red Sox (85-73), Cubs (88-71)

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 61.26%
• Red Sox Win Probability: 38.74%

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Baltimore Orioles at New York Yankees

Game Info

• When: 4:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: FOX
• Probable Pitchers: Carlos Rodon vs. Brandon Young
• Records: Yankees (91-67), Orioles (78-81)

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Chicago Cubs at Boston Red Sox

Game Info

• When: 6:05 p.m. ET
• Where: Fenway Park
• TV Channel: NESN and MARQ
• Probable Pitchers: Jake Bennett vs. Clay Holmes
• Records: Red Sox (85-73), Cubs (88-71)

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 55.68%
• Red Sox Win Probability: 44.32%

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Tampa Bay Rays at Philadelphia Phillies Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Citizens Bank Park
• TV Channel: NBCS-PH and RAYS
• Probable Pitchers: Cristopher Sanchez vs. Freddy Peralta
• Records: Phillies (87-72), Rays (96-62)
• Phillies Moneyline Odds: -162
• Rays Moneyline Odds: +136

numberFire Prediction

• numberFire Predicted Favorite: Phillies
• Phillies Win Probability: 54.90%
• Rays Win Probability: 45.10%

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Pittsburgh Pirates at Detroit Tigers Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Comerica Park
• TV Channel: DSN and SportsNet PT
• Probable Pitchers: Jackson Jobe vs. Bubba Chandler
• Records: Tigers (74-85), Pirates (81-78)
• Tigers Moneyline Odds: -108
• Pirates Moneyline Odds: -108

numberFire Prediction

• numberFire Predicted Favorite: Tigers
• Tigers Win Probability: 51.65%
• Pirates Win Probability: 48.35%

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New York Mets at Washington Nationals Odds, Lines & Predictions

Game Info

• When: 6:45 p.m. ET
• Where: Nationals Park
• TV Channel: NATS and WPIX
• Probable Pitchers: Andrew Alvarez vs.
• Records: Nationals (75-84), Mets (73-86)
• Mets Moneyline Odds: -134
• Nationals Moneyline Odds: +114

numberFire Prediction

• numberFire Predicted Favorite: Nationals
• Nationals Win Probability: 58.91%
• Mets Win Probability: 41.09%

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Baltimore Orioles at New York Yankees

Game Info

• When: 7:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: YES and MASN
• Probable Pitchers: Will Warren vs. Trevor Rogers
• Records: Yankees (91-67), Orioles (78-81)

numberFire Prediction

• numberFire Predicted Favorite: Yankees
• Yankees Win Probability: 58.89%
• Orioles Win Probability: 41.11%

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Cincinnati Reds at Toronto Blue Jays Odds, Lines & Predictions

Game Info

• When: 7:07 p.m. ET
• Where: Rogers Centre
• TV Channel: SNET and CINR
• Probable Pitchers: José Soriano vs. Nick Lodolo
• Records: Blue Jays (77-82), Reds (73-85)
• Blue Jays Moneyline Odds: -136
• Reds Moneyline Odds: +116

numberFire Prediction

• numberFire Predicted Favorite: Blue Jays
• Blue Jays Win Probability: 64.95%
• Reds Win Probability: 35.05%

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Atlanta Braves at Miami Marlins Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: loanDepot park
• TV Channel: MIAM and BravesVsn
• Probable Pitchers: Eury Pérez vs. Grant Holmes
• Records: Marlins (78-81), Braves (93-65)
• Braves Moneyline Odds: -124
• Marlins Moneyline Odds: +106

numberFire Prediction

• numberFire Predicted Favorite: Marlins
• Marlins Win Probability: 56.83%
• Braves Win Probability: 43.17%

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Cleveland Guardians at Kansas City Royals Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Kauffman Stadium
• TV Channel: ROYL and CLEG
• Probable Pitchers: Noah Cameron vs. Gavin Williams
• Records: Royals (68-91), Guardians (82-76)
• Guardians Moneyline Odds: -142
• Royals Moneyline Odds: +120

numberFire Prediction

• numberFire Predicted Favorite: Royals
• Royals Win Probability: 56.20%
• Guardians Win Probability: 43.80%

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Colorado Rockies at Chicago White Sox Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Rate Field
• TV Channel: CHSN and COLR
• Probable Pitchers: Sean Burke vs. José Quintana
• Records: White Sox (82-77), Rockies (57-102)
• White Sox Moneyline Odds: -235
• Rockies Moneyline Odds: +194

numberFire Prediction

• numberFire Predicted Favorite: White Sox
• White Sox Win Probability: 62.10%
• Rockies Win Probability: 37.90%

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St. Louis Cardinals at Milwaukee Brewers Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: American Family Field
• TV Channel: BREW and CARD
• Probable Pitchers: Robert Gasser vs. Michael McGreevy
• Records: Brewers (100-59), Cardinals (77-82)
• Brewers Moneyline Odds: -172
• Cardinals Moneyline Odds: +144

numberFire Prediction

• numberFire Predicted Favorite: Brewers
• Brewers Win Probability: 64.46%
• Cardinals Win Probability: 35.54%

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Texas Rangers at Minnesota Twins Odds, Lines & Predictions

Game Info

• When: 8:10 p.m. ET
• Where: Target Field
• TV Channel: MNNT and RSN
• Probable Pitchers: Joe Ryan vs. Jacob deGrom
• Records: Twins (75-84), Rangers (79-80)
• Twins Moneyline Odds: -108
• Rangers Moneyline Odds: -108

numberFire Prediction

• numberFire Predicted Favorite: Twins
• Twins Win Probability: 58.87%
• Rangers Win Probability: 41.13%

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Houston Astros at Athletics

Game Info

• When: 9:40 p.m. ET
• Where: Sutter Health Park
• TV Channel: NBCS-CA and SCHN
• Probable Pitchers: Jacob Lopez vs. Hayden Wesneski
• Records: Athletics (63-95), Astros (78-80)

numberFire Prediction

• numberFire Predicted Favorite: Athletics
• Athletics Win Probability: 50.08%
• Astros Win Probability: 49.92%

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Arizona Diamondbacks at San Diego Padres Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: Petco Park
• TV Channel: SDPA and ARID
• Probable Pitchers: Casey Mize vs. Zac Gallen
• Records: Padres (88-70), Diamondbacks (85-74)
• Padres Moneyline Odds: -132
• Diamondbacks Moneyline Odds: +112

numberFire Prediction

• numberFire Predicted Favorite: Padres
• Padres Win Probability: 64.13%
• Diamondbacks Win Probability: 35.87%

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Los Angeles Angels at Seattle Mariners Odds, Lines & Predictions

Game Info

• When: 10:10 p.m. ET
• Where: T-Mobile Park
• TV Channel: SEAM and ABTV
• Probable Pitchers: Bryce Miller vs. Reid Detmers
• Records: Mariners (74-84), Angels (60-98)
• Mariners Moneyline Odds: -132
• Angels Moneyline Odds: +112

numberFire Prediction

• numberFire Predicted Favorite: Mariners
• Mariners Win Probability: 50.67%
• Angels Win Probability: 49.33%

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Los Angeles Dodgers at San Francisco Giants Odds, Lines & Predictions

Game Info

• When: 10:15 p.m. ET
• Where: Oracle Park
• TV Channel: NBCS-BA and SportsNet LA
• Probable Pitchers: Yunior Marté vs. Tarik Skubal
• Records: Giants (65-94), Dodgers (97-61)
• Dodgers Moneyline Odds: -375
• Giants Moneyline Odds: +300

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 66.26%
• Giants Win Probability: 33.74%

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All MLB win probability predictions and picks are according to numberFire.