Wednesday’s MLB Odds, Betting Lines and Predictions - Sept. 23

In a Wednesday MLB schedule that features a lot of thrilling contests, the Milwaukee Brewers versus the Philadelphia Phillies is a game to see. For predictions on every game on the slate, check out the article below.

Today's MLB Odds and Predictions

Washington Nationals at Detroit Tigers Odds, Lines & Predictions

Game Info

• When: 1:10 p.m. ET
• Where: Comerica Park
• TV Channel: DSN and NATS
• Probable Pitchers: Framber Valdez vs. Richard Lovelady
• Records: Tigers (74-85), Nationals (75-84)
• Tigers Moneyline Odds: -166
• Nationals Moneyline Odds: +140

numberFire Prediction

• numberFire Predicted Favorite: Tigers
• Tigers Win Probability: 63.15%
• Nationals Win Probability: 36.85%

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Toronto Blue Jays at Baltimore Orioles Odds, Lines & Predictions

Game Info

• When: 1:35 p.m. ET
• Where: Oriole Park at Camden Yards
• TV Channel: MASN and SNET
• Probable Pitchers: Chris Bassitt vs. Max Scherzer
• Records: Orioles (78-81), Blue Jays (77-82)
• Orioles Moneyline Odds: -126
• Blue Jays Moneyline Odds: +108

numberFire Prediction

• numberFire Predicted Favorite: Orioles
• Orioles Win Probability: 58.79%
• Blue Jays Win Probability: 41.21%

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Minnesota Twins at San Francisco Giants Odds, Lines & Predictions

Game Info

• When: 3:45 p.m. ET
• Where: Oracle Park
• TV Channel: NBCS-BA and MNNT
• Probable Pitchers: César Perdomo vs. Connor Prielipp
• Records: Giants (65-94), Twins (75-84)
• Twins Moneyline Odds: -152
• Giants Moneyline Odds: +128

numberFire Prediction

• numberFire Predicted Favorite: Twins
• Twins Win Probability: 53.96%
• Giants Win Probability: 46.04%

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Toronto Blue Jays at Baltimore Orioles Odds, Lines & Predictions

Game Info

• When: 6:35 p.m. ET
• Where: Oriole Park at Camden Yards
• TV Channel: MASN and SNET
• Probable Pitchers: Trey Gibson vs. CJ Van Eyk
• Records: Orioles (78-81), Blue Jays (77-82)
• Orioles Moneyline Odds: -120
• Blue Jays Moneyline Odds: +102

numberFire Prediction

• numberFire Predicted Favorite: Blue Jays
• Blue Jays Win Probability: 51.95%
• Orioles Win Probability: 48.05%

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St. Louis Cardinals at Pittsburgh Pirates Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: PNC Park
• TV Channel: SportsNet PT and CARD
• Probable Pitchers: Lake Bachar vs. Matthew Liberatore
• Records: Pirates (80-77), Cardinals (76-81)
• Pirates Moneyline Odds: -134
• Cardinals Moneyline Odds: +114

numberFire Prediction

• numberFire Predicted Favorite: Pirates
• Pirates Win Probability: 62.42%
• Cardinals Win Probability: 37.58%

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Milwaukee Brewers at Philadelphia Phillies Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Citizens Bank Park
• TV Channel: NBCS-PH and BREW
• Probable Pitchers: Aaron Nola vs. Logan Henderson
• Records: Phillies (87-70), Brewers (98-59)
• Brewers Moneyline Odds: -122
• Phillies Moneyline Odds: +104

numberFire Prediction

• numberFire Predicted Favorite: Brewers
• Brewers Win Probability: 58.07%
• Phillies Win Probability: 41.93%

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Tampa Bay Rays at New York Yankees Odds, Lines & Predictions

Game Info

• When: 7:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: Amazon Prime Video and RAYS
• Probable Pitchers: Gerrit Cole vs. Mason Englert
• Records: Yankees (90-67), Rays (96-61)
• Yankees Moneyline Odds: -144
• Rays Moneyline Odds: +122

numberFire Prediction

• numberFire Predicted Favorite: Yankees
• Yankees Win Probability: 52.65%
• Rays Win Probability: 47.35%

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Cleveland Guardians at Boston Red Sox Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: Fenway Park
• TV Channel: ESPN
• Probable Pitchers: Sonny Gray vs. Foster Griffin
• Records: Red Sox (84-73), Guardians (82-75)
• Red Sox Moneyline Odds: -142
• Guardians Moneyline Odds: +120

numberFire Prediction

• numberFire Predicted Favorite: Red Sox
• Red Sox Win Probability: 59.68%
• Guardians Win Probability: 40.32%

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Cincinnati Reds at Atlanta Braves Odds, Lines & Predictions

Game Info

• When: 7:15 p.m. ET
• Where: Truist Park
• TV Channel: BravesVsn and CINR
• Probable Pitchers: Chris Sale vs. Andrew Abbott
• Records: Braves (92-65), Reds (73-84)
• Braves Moneyline Odds: -270
• Reds Moneyline Odds: +220

numberFire Prediction

• numberFire Predicted Favorite: Braves
• Braves Win Probability: 73.24%
• Reds Win Probability: 26.76%

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Miami Marlins at Chicago Cubs Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Wrigley Field
• TV Channel: MARQ and MIAM
• Probable Pitchers: Kevin Gausman vs. Ryan Gusto
• Records: Cubs (87-70), Marlins (77-80)
• Cubs Moneyline Odds: -180
• Marlins Moneyline Odds: +152

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 63.30%
• Marlins Win Probability: 36.70%

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Chicago White Sox at Kansas City Royals Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Kauffman Stadium
• TV Channel: ROYL and CHSN
• Probable Pitchers: Seth Lugo vs. Bryan Hudson
• Records: Royals (67-90), White Sox (81-76)
• White Sox Moneyline Odds: -116
• Royals Moneyline Odds: -102

numberFire Prediction

• numberFire Predicted Favorite: White Sox
• White Sox Win Probability: 56.28%
• Royals Win Probability: 43.72%

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New York Mets at Texas Rangers Odds, Lines & Predictions

Game Info

• When: 8:05 p.m. ET
• Where: Globe Life Field
• TV Channel: RSN and SNY
• Probable Pitchers: Cody Bradford vs. Nolan McLean
• Records: Rangers (78-79), Mets (72-85)
• Rangers Moneyline Odds: -108
• Mets Moneyline Odds: -108

numberFire Prediction

• numberFire Predicted Favorite: Mets
• Mets Win Probability: 50.54%
• Rangers Win Probability: 49.46%

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Arizona Diamondbacks at Colorado Rockies Odds, Lines & Predictions

Game Info

• When: 8:40 p.m. ET
• Where: Coors Field
• TV Channel: COLR and ARID
• Probable Pitchers: Mason Adams vs. Merrill Kelly
• Records: Rockies (57-100), Diamondbacks (83-74)
• Diamondbacks Moneyline Odds: -164
• Rockies Moneyline Odds: +138

numberFire Prediction

• numberFire Predicted Favorite: Diamondbacks
• Diamondbacks Win Probability: 56.86%
• Rockies Win Probability: 43.14%

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Los Angeles Angels at Athletics Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: Sutter Health Park
• TV Channel: NBCS-CA and ABTV
• Probable Pitchers: Jeffrey Springs vs. Walbert Ureña
• Records: Athletics (62-95), Angels (60-97)
• Angels Moneyline Odds: -136
• Athletics Moneyline Odds: +116

numberFire Prediction

• numberFire Predicted Favorite: Athletics
• Athletics Win Probability: 50.91%
• Angels Win Probability: 49.09%

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San Diego Padres at Los Angeles Dodgers Odds, Lines & Predictions

Game Info

• When: 10:10 p.m. ET
• Where: Dodger Stadium
• TV Channel: SportsNet LA and SDPA
• Probable Pitchers: Yoshinobu Yamamoto vs. Robbie Ray
• Records: Dodgers (97-60), Padres (87-70)
• Dodgers Moneyline Odds: -225
• Padres Moneyline Odds: +188

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 66.18%
• Padres Win Probability: 33.82%

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Houston Astros at Seattle Mariners Odds, Lines & Predictions

Game Info

• When: 10:10 p.m. ET
• Where: T-Mobile Park
• TV Channel: ESPN
• Probable Pitchers: George Kirby vs. Ethan Pecko
• Records: Mariners (73-84), Astros (78-79)
• Mariners Moneyline Odds: -130
• Astros Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Mariners
• Mariners Win Probability: 60.19%
• Astros Win Probability: 39.81%

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All MLB win probability predictions and picks are according to numberFire.