Wednesday’s MLB Odds, Betting Lines and Predictions - Sept. 23

There are several strong matchups on Wednesday's MLB schedule, including the Milwaukee Brewers squaring off against the Philadelphia Phillies. Take a look at at the article below, where we provide predictions for each game.

Today's MLB Odds and Predictions

Washington Nationals at Detroit Tigers Odds, Lines & Predictions

Game Info

• When: 1:10 p.m. ET
• Where: Comerica Park
• TV Channel: DSN and NATS
• Probable Pitchers: Framber Valdez vs.
• Records: Tigers (74-83), Nationals (73-84)
• Tigers Moneyline Odds: -190
• Nationals Moneyline Odds: +160

numberFire Prediction

• numberFire Predicted Favorite: Tigers
• Tigers Win Probability: 54.00%
• Nationals Win Probability: 46.00%

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Toronto Blue Jays at Baltimore Orioles Odds, Lines & Predictions

Game Info

• When: 1:35 p.m. ET
• Where: Oriole Park at Camden Yards
• TV Channel: MASN and SNET
• Probable Pitchers: Chris Bassitt vs. Max Scherzer
• Records: Orioles (76-81), Blue Jays (77-80)
• Orioles Moneyline Odds: -126
• Blue Jays Moneyline Odds: +108

numberFire Prediction

• numberFire Predicted Favorite: Orioles
• Orioles Win Probability: 58.34%
• Blue Jays Win Probability: 41.66%

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Minnesota Twins at San Francisco Giants Odds, Lines & Predictions

Game Info

• When: 3:45 p.m. ET
• Where: Oracle Park
• TV Channel: NBCS-BA and MNNT
• Probable Pitchers: César Perdomo vs.
• Records: Giants (65-92), Twins (73-84)
• Twins Moneyline Odds: -148
• Giants Moneyline Odds: +126

numberFire Prediction

• numberFire Predicted Favorite: Giants
• Giants Win Probability: 50.21%
• Twins Win Probability: 49.79%

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Toronto Blue Jays at Baltimore Orioles

Game Info

• When: 6:35 p.m. ET
• Where: Oriole Park at Camden Yards
• TV Channel: MASN and SNET
• Probable Pitchers: vs.
• Records: Orioles (76-81), Blue Jays (77-80)

numberFire Prediction

• numberFire Predicted Favorite: Orioles
• Orioles Win Probability: 52.17%
• Blue Jays Win Probability: 47.83%

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Milwaukee Brewers at Philadelphia Phillies Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Citizens Bank Park
• TV Channel: NBCS-PH and BREW
• Probable Pitchers: Aaron Nola vs. Logan Henderson
• Records: Phillies (86-70), Brewers (98-58)
• Brewers Moneyline Odds: -136
• Phillies Moneyline Odds: +116

numberFire Prediction

• numberFire Predicted Favorite: Brewers
• Brewers Win Probability: 58.14%
• Phillies Win Probability: 41.86%

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St. Louis Cardinals at Pittsburgh Pirates

Game Info

• When: 6:40 p.m. ET
• Where: PNC Park
• TV Channel: SportsNet PT and CARD
• Probable Pitchers: vs. Matthew Liberatore
• Records: Pirates (80-77), Cardinals (76-81)

numberFire Prediction

• numberFire Predicted Favorite: Pirates
• Pirates Win Probability: 57.35%
• Cardinals Win Probability: 42.65%

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Tampa Bay Rays at New York Yankees Odds, Lines & Predictions

Game Info

• When: 7:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: Amazon Prime Video and RAYS
• Probable Pitchers: Gerrit Cole vs. Ian Seymour
• Records: Yankees (90-66), Rays (95-61)
• Yankees Moneyline Odds: -152
• Rays Moneyline Odds: +128

numberFire Prediction

• numberFire Predicted Favorite: Rays
• Rays Win Probability: 53.16%
• Yankees Win Probability: 46.84%

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Cleveland Guardians at Boston Red Sox Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: Fenway Park
• TV Channel: ESPN
• Probable Pitchers: Sonny Gray vs. Foster Griffin
• Records: Red Sox (84-72), Guardians (81-75)
• Red Sox Moneyline Odds: -142
• Guardians Moneyline Odds: +120

numberFire Prediction

• numberFire Predicted Favorite: Red Sox
• Red Sox Win Probability: 59.47%
• Guardians Win Probability: 40.53%

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Cincinnati Reds at Atlanta Braves Odds, Lines & Predictions

Game Info

• When: 7:15 p.m. ET
• Where: Truist Park
• TV Channel: BravesVsn and CINR
• Probable Pitchers: Chris Sale vs. Andrew Abbott
• Records: Braves (92-64), Reds (72-84)
• Braves Moneyline Odds: -255
• Reds Moneyline Odds: +210

numberFire Prediction

• numberFire Predicted Favorite: Braves
• Braves Win Probability: 72.86%
• Reds Win Probability: 27.14%

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Miami Marlins at Chicago Cubs Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Wrigley Field
• TV Channel: MARQ and MIAM
• Probable Pitchers: Kevin Gausman vs. Ryan Gusto
• Records: Cubs (87-69), Marlins (76-80)
• Cubs Moneyline Odds: -178
• Marlins Moneyline Odds: +150

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 59.36%
• Marlins Win Probability: 40.64%

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Chicago White Sox at Kansas City Royals Odds, Lines & Predictions

Game Info

• When: 7:40 p.m. ET
• Where: Kauffman Stadium
• TV Channel: ROYL and CHSN
• Probable Pitchers: Seth Lugo vs. Erick Fedde
• Records: Royals (67-89), White Sox (80-76)
• White Sox Moneyline Odds: -116
• Royals Moneyline Odds: -102

numberFire Prediction

• numberFire Predicted Favorite: Royals
• Royals Win Probability: 50.95%
• White Sox Win Probability: 49.05%

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New York Mets at Texas Rangers

Game Info

• When: 8:05 p.m. ET
• Where: Globe Life Field
• TV Channel: RSN and SNY
• Probable Pitchers: vs. Nolan McLean
• Records: Rangers (78-78), Mets (71-85)

numberFire Prediction

• numberFire Predicted Favorite: Rangers
• Rangers Win Probability: 55.28%
• Mets Win Probability: 44.72%

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Arizona Diamondbacks at Colorado Rockies Odds, Lines & Predictions

Game Info

• When: 8:40 p.m. ET
• Where: Coors Field
• TV Channel: COLR and ARID
• Probable Pitchers: Mason Adams vs. Merrill Kelly
• Records: Rockies (57-99), Diamondbacks (82-74)
• Diamondbacks Moneyline Odds: -158
• Rockies Moneyline Odds: +134

numberFire Prediction

• numberFire Predicted Favorite: Diamondbacks
• Diamondbacks Win Probability: 58.95%
• Rockies Win Probability: 41.05%

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Los Angeles Angels at Athletics Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: Sutter Health Park
• TV Channel: NBCS-CA and ABTV
• Probable Pitchers: Jeffrey Springs vs. Walbert Ureña
• Records: Athletics (61-95), Angels (60-96)
• Angels Moneyline Odds: -130
• Athletics Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Athletics
• Athletics Win Probability: 50.63%
• Angels Win Probability: 49.37%

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Houston Astros at Seattle Mariners

Game Info

• When: 10:10 p.m. ET
• Where: T-Mobile Park
• TV Channel: ESPN
• Probable Pitchers: George Kirby vs.
• Records: Mariners (73-83), Astros (77-79)

numberFire Prediction

• numberFire Predicted Favorite: Mariners
• Mariners Win Probability: 61.92%
• Astros Win Probability: 38.08%

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San Diego Padres at Los Angeles Dodgers Odds, Lines & Predictions

Game Info

• When: 10:10 p.m. ET
• Where: Dodger Stadium
• TV Channel: SportsNet LA and SDPA
• Probable Pitchers: Yoshinobu Yamamoto vs. Robbie Ray
• Records: Dodgers (96-60), Padres (87-69)
• Dodgers Moneyline Odds: -215
• Padres Moneyline Odds: +180

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 61.15%
• Padres Win Probability: 38.85%

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All MLB win probability predictions and picks are according to numberFire.