Missouri vs Kansas Prediction, Odds, Picks, Best Bets for Week 2 2026

The college football schedule on Friday includes the Missouri Tigers facing the Kansas Jayhawks.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important info about today's NCAA football betting odds.

Missouri vs Kansas Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Missouri: (-205) | Kansas: (+168)
• Spread: Missouri: -4.5 (-110) | Kansas: +4.5 (-110)
• Total: 51.5 -- Over: (-110) | Under: (-110)

Missouri vs Kansas Betting Trends

• Missouri has no wins against the spread this season.
• Missouri is winless ATS (0-1) as a 4.5-point favorite or greater this year.
• Every Missouri game has hit the over this season.
• Kansas has but one win versus the spread this season.
• One of Kansas' one games has gone over the point total.

Missouri vs Kansas Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (63%)

Missouri vs Kansas Point Spread

Missouri is favored by 4.5 points against Kansas. Missouri is -110 to cover the spread, while Kansas is -110.

Missouri vs Kansas Over/Under

Missouri versus Kansas on Sept. 11 has an over/under of 51.5 points, with the over -110 and the under -110.

Missouri vs Kansas Moneyline

The Missouri vs Kansas moneyline has Missouri as a -205 favorite, while Kansas is a +168 underdog.

Missouri vs. Kansas Points Insights

• The Tigers' average implied point total last season was 3.2 more points than their implied total in Friday's game (31.2 implied points on average compared to 28 implied points in this game).
• The average implied point total last season for the Jayhawks (34.0) is 10.0 more points than the team's implied total in this matchup (24).

Missouri vs. Kansas Game Info

• Game day: Friday, September 11, 2026
• Game time: 8 p.m. ET
• TV channel: FOX
• Location: Lawrence, Kansas
• Stadium: David Booth Kansas Memorial Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Missouri vs. Kansas analysis on FanDuel Research.