Michigan State vs Toledo Prediction, Odds, Picks, Best Bets for Week 1 2026

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The Michigan State Spartans will face the Toledo Rockets in college football action on Friday.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Michigan State vs Toledo Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Michigan State: (-429) | Toledo: (+330)
Spread: Michigan State: -10.5 (-105) | Toledo: +10.5 (-115)
Total: 47.5 -- Over: (-106) | Under: (-114)

Michigan State was 7-5-0 against the spread last year.
Michigan State didn't have a win ATS (0-2) as favorites of 10.5 points or greater last year.
Last season, seven of Michigan State's 12 games hit the over.
Toledo posted a 10-3-0 record against the spread last season.
Toledo did not lose ATS (1-0) as underdogs of 10.5 points or greater last season.
There were seven Toledo games (out of 13) that went over the total last season.

All college football win probability predictions and picks are according to numberFire.
Prediction: Rockets win (59.3%)

Toledo is a 10.5-point underdog against Michigan State. Toledo is -115 to cover the spread, and Michigan State is -105.

An over/under of 47.5 has been set for Michigan State-Toledo on Sept. 4, with the over being -106 and the under -114.

Michigan State is the favorite, -429 on the moneyline, while Toledo is a +330 underdog.

The Spartans had an average implied point total of 31.3 last season, which is 2.3 points higher than their implied total in Friday's game (29).
The Rockets' average implied point total last season (31.5 points) is 12.5 points higher than their implied total in this matchup (19 points).

Check out even more in-depth Michigan State vs. Toledo analysis on FanDuel Research.

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