Michigan State vs Eastern Michigan Prediction, Odds, Picks, Best Bets for Week 2 2026

The Michigan State Spartans versus the Eastern Michigan Eagles is on the college football schedule for Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Michigan State vs Eastern Michigan Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Michigan State: (-901) | Eastern Michigan: (+590)
• Spread: Michigan State: -17.5 (-106) | Eastern Michigan: +17.5 (-114)
• Total: 49.5 -- Over: (-110) | Under: (-110)

Michigan State vs Eastern Michigan Betting Trends

• Michigan State hasn't won a game against the spread this season.
• All one of Michigan State's games have gone over the point total this season.
• Eastern Michigan has but one win versus the spread this season.
• None of Eastern Michigan's two games has hit the over in 2026.

Michigan State vs Eastern Michigan Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Spartans win (85.6%)

Michigan State vs Eastern Michigan Point Spread

Eastern Michigan is a 17.5-point underdog against Michigan State. Eastern Michigan is -114 to cover the spread, and Michigan State is -106.

Michigan State vs Eastern Michigan Over/Under

The Michigan State-Eastern Michigan game on Sept. 12 has been given an over/under of 49.5 points. The over is -110 and the under is -110.

Michigan State vs Eastern Michigan Moneyline

Eastern Michigan is a +590 underdog on the moneyline, while Michigan State is a -901 favorite.

Michigan State vs. Eastern Michigan Points Insights

• The average implied total for the Spartans last season was 31.3 points, 2.7 fewer points than their implied total of 34 points in Saturday's game.
• The average implied point total last season for the Eagles (31.0) is 15.0 more points than the team's implied total in this matchup (16).

Michigan State vs. Eastern Michigan Game Info

• Game day: Saturday, September 12, 2026
• Game time: 3:30 p.m. ET
• TV channel: BTN
• Location: East Lansing, Michigan
• Stadium: Spartan Stadium

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Check out even more in-depth Michigan State vs. Eastern Michigan analysis on FanDuel Research.