Michigan State vs East Carolina College Basketball Prediction, Odds, Picks, Best Bets for Nov. 25

The Michigan State Spartans (5-0) will host the East Carolina Pirates (2-3) after winning four home games in a row.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Michigan State vs. East Carolina Game Info and Odds

• Game day: Tuesday, November 25, 2025
• Game time: 1 p.m. ET
• TV channel: Fox Sports 2
• Location: Cypress Lake, Florida
• Arena: Suncoast Credit Union Arena

Michigan State vs. East Carolina Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Michigan State win (91.8%)

Before making a bet on Tuesday's Michigan State-East Carolina spread (Michigan State -20.5) or over/under (142.5 points), take a look at the betting insights and trends below.

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Michigan State vs. East Carolina: ATS Betting Stats and Trends

• Michigan State has covered twice in five matchups with a spread this season.
• East Carolina has not won against the spread this year in four games with a spread.
• The Spartans sported a worse record against the spread at home (10-6-0) than they did in road games (7-2-0) last season.
• Against the spread last year, the Pirates had better results away (5-5-0) than at home (7-9-0).

Michigan State vs. East Carolina: Moneyline Betting Stats

• Michigan State has yet to lose any of the three games it has been chosen as the moneyline favorite in this season.
• The Spartans have been listed as a favorite of -4545 or more on two occasions this season and won both games.
• East Carolina has been the moneyline underdog only two other times so far this season, and it lost both games.
• The Pirates have never played a game this season with moneyline odds of +1600 or longer.
• Michigan State has an implied victory probability of 97.8% according to the moneyline set by sportsbooks for this matchup.

Michigan State vs. East Carolina Head-to-Head Comparison

• Michigan State is outscoring opponents by 15.6 points per game with a +78 scoring differential overall. It puts up 79 points per game (180th in college basketball) and gives up 63.4 per contest (33rd in college basketball).
• Jaxon Kohler's team-leading 15.2 points per game ranks 310th in the nation.
• East Carolina puts up 72 points per game (290th in college basketball) while giving up 81.6 per outing (312th in college basketball). It has a -48 scoring differential and has been outscored by 9.6 points per game.
• East Carolina's leading scorer, Joran Riley, is 89th in the nation, scoring 18.5 points per game.
• The 40.6 rebounds per game the Spartans average rank 23rd in the nation, and are 14 more than the 26.6 their opponents collect per outing.
• Kohler leads the Spartans with 9.8 rebounds per game (36th in college basketball play).
• The 34 rebounds per game the Pirates accumulate rank 183rd in the nation, 2.6 more than the 31.4 their opponents pull down.
• Giovanni Emejuru paces the team with 9.8 rebounds per game (36th in college basketball).
• Michigan State ranks 136th in college basketball with 100.6 points scored per 100 possessions, and 38th in college basketball defensively with 80.7 points conceded per 100 possessions.
• The Pirates rank 308th in college basketball with 88.7 points scored per 100 possessions, and 314th defensively with 100.5 points conceded per 100 possessions.

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