Lakers vs. Clippers Prediction, Odds, Picks, Best Bets for Nov. 25

Lakers vs. Clippers Game Info

• Date: Tuesday, November 25, 2025
• Time: 11 p.m. ET
• Venue: Crypto.com Arena -- Los Angeles, California
• Coverage: NBC/Peacock

The Los Angeles Lakers (12-4) are 6-point favorites as they look to extend a three-game home win streak when they host the Los Angeles Clippers (5-12) on Tuesday, November 25, 2025 at Crypto.com Arena. The game airs at 11 p.m. ET on NBC/Peacock. The matchup has an over/under of 229.5 points.

Lakers vs. Clippers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Lakers vs. Clippers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Lakers win (59.7%)

Lakers vs. Clippers Betting Trends

• The Lakers are 11-5-0 against the spread this season.
• Against the spread, the Clippers are 5-12-0 this year.
• This season, Lakers games have hit the over 10 times out of 17 chances.
• The Clippers have gone over the point total 58.8% of the time this season (10 of 17 games with a set point total).
• The Lakers have covered the spread in a lower percentage of their home games than road games. They have covered four times in six games when playing at home, and they've covered seven times in 10 games on the road.
• At home, the Lakers exceed the total 100% of the time (six of six games). They've hit the over in 40% of away games (four of 10 contests).
• The Clippers have performed better against the spread away (4-5-0) than at home (1-7-0) this year.
• Looking at the over/under, Clippers games have gone over more frequently at home (five of eight, 62.5%) than on the road (five of nine, 55.6%).

Lakers Leaders

• Luka Doncic is averaging 34.5 points, 8.9 assists and 8.8 boards.
• Austin Reaves' numbers on the season are 27.6 points, 5.5 rebounds and 7.3 assists per contest, shooting 48.4% from the field and 31.1% from beyond the arc, with an average of 2.5 made treys.
• Jake Laravia's numbers on the season are 10.3 points, 4.3 boards and 2.3 assists per contest, shooting 48% from the field and 34.6% from downtown, with an average of 1.1 made treys.
• Rui Hachimura is averaging 15 points, 1.1 assists and 3.9 rebounds.
• Marcus Smart is averaging 9.5 points, 2.2 rebounds and 2.9 assists.

Clippers Leaders

• James Harden's numbers on the season are 27.8 points, 5.8 boards and 8.4 assists per game. He is also draining 45.3% of his shots from the floor and 38.8% from beyond the arc, with an average of 3.9 triples (third in NBA).
• The Clippers get 17 points per game from Ivica Zubac, plus 11.6 boards and 2.4 assists.
• The Clippers receive 11.2 points per game from John Collins, plus 4.8 boards and 0.5 assists.
• Per game, Kris Dunn gives the Clippers 7.1 points, 2.6 rebounds and 2.6 assists, plus 1.4 steals and 0.2 blocks.
• Per game, Kawhi Leonard provides the Clippers 23.7 points, 5.3 rebounds and 3.3 assists, plus 2.6 steals and 0.6 blocks.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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