Mets vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 6:12 p.m.

On Friday in MLB, the Washington Nationals are up against the New York Mets.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Nationals vs Mets Game Info

• Washington Nationals (75-84) vs. New York Mets (73-86)
• Date: Friday, September 25, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and WPIX

Nationals vs Mets Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: WSH: (-108) | NYM: (-108)
• Spread: WSH: +1.5 (-182) | NYM: -1.5 (+150)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Nationals vs Mets Probable Starting Pitchers

Probable Pitchers: Andrew Alvarez (Nationals) - 2-6, 3.17 ERA vs Jefry Yan (Mets) - 2-1, 4.34 ERA

This contest's pitching matchup is set, as the Nationals will send Andrew Alvarez (2-6) to the mound, while Jefry Yan (2-1) will get the nod for the Mets. When Alvarez starts, his team is 6-10-0 against the spread this season. When Alvarez starts a game and his team is the favorite on the moneyline, they have a record of 3-3. Yan never pitched as a moneyline underdog a season ago.

Nationals vs Mets Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (56.2%)

Nationals vs Mets Moneyline

• New York is the underdog, -108 on the moneyline, while Washington is a -108 favorite at home.

Nationals vs Mets Spread

Nationals vs Mets Over/Under

• Nationals versus Mets, on Sept. 25, has an over/under of 8.5, with the over being -105 and the under -115.

Bet on Washington Nationals vs. New York Mets on FanDuel today!

Nationals vs Mets Betting Trends

• The Nationals have been favorites in 32 games this season and have come away with the win 18 times (56.2%) in those contests.
• This year Washington has won 20 of 35 games when listed as at least -108 on the moneyline.
• Contests with the Nationals have gone over the total set by oddsmakers in 81 of 155 chances this season.
• The Nationals have an against the spread record of 85-70-0 in 155 games with a line this season.
• The Mets have won 26 of the 71 games they were listed as the moneyline underdog this season (36.6%).
• When playing as a moneyline underdog with odds of -108 or longer, New York has a 26-46 record (winning just 36.1% of its games).
• The Mets have played in 155 games with a set over/under, and have combined with their opponents to go over the total 73 times (73-73-9).
• The Mets have a 72-83-0 record ATS this season (covering 46.5% of the time).

Nationals Player Leaders

• C.J. Abrams has an OPS of .838, fueled by an OBP of .338 and a team-best slugging percentage of .500 this season. He has a .262 batting average.
• He ranks 54th in batting average, 56th in on-base percentage, and 15th in slugging among qualified batters in baseball.
• Abrams hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .222 with three home runs, three walks and six RBIs.
• James Wood leads the Nationals in OBP (.385) and total hits (132) this season. He's batting .262 while slugging .505.
• Among qualified batters, he is 54th in batting average, fifth in on-base percentage and 14th in slugging percentage.
• Daylen Lile has collected 146 base hits, an OBP of .299 and a slugging percentage of .433 this season.
• Jacob Young has 10 home runs, 49 RBI and a batting average of .249 this season.

Mets Player Leaders

• Juan Soto has 11 doubles, two triples, 27 home runs and 77 walks while batting .274. He's slugging .522 with an on-base percentage of .393.
• Carson Benge has racked up 160 hits with a .338 on-base percentage to lead his team in both. He has a batting average of .274 while slugging .419.
• Including all qualifying players, he is 37th in batting average, 56th in on-base percentage and 72nd in slugging percentage.
• Bo Bichette has put up a team-best .386 slugging percentage.
• Francisco Lindor is batting .225 with 12 doubles, four triples, 20 home runs and 44 walks.

Nationals vs Mets Head to Head

• 8/16/2026: 4-3 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/15/2026: 5-4 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +124)
• 8/14/2026: 4-1 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: +106)
• 5/21/2026: 2-1 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/20/2026: 8-4 WSH (Favorite: Mets, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/19/2026: 9-6 WSH (Favorite: Mets, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/18/2026: 16-7 NYM (Favorite: Mets, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/30/2026: 5-4 WSH (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/29/2026: 14-2 WSH (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/28/2026: 8-0 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)

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