Louisville vs Boston College College Basketball Prediction, Odds, Picks, Best Bets for Jan. 10

ACC action features the No. 20 Louisville Cardinals (11-4, 1-2 ACC) at home against the Boston College Eagles (7-8, 0-2 ACC) on Saturday, January 10, 2026 at 12 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Boston College Game Info and Odds

• Game day: Saturday, January 10, 2026
• Game time: 12 p.m. ET
• TV channel: The CW Network
• Location: Louisville, Kentucky
• Arena: KFC Yum! Center

Louisville vs. Boston College Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Louisville win (92.6%)

Louisville is a 20.5-point favorite over Boston College on Saturday and the over/under is set at 149.5 points. Here are a few betting trends and insights before you decide to wager on the outing.

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Louisville vs. Boston College: ATS Betting Stats and Trends

• Louisville has put together a 9-6-0 record against the spread this season.
• Boston College has put together a 4-11-0 ATS record so far this season.
• In home games, the Cardinals own a better record against the spread (6-3-0) compared to their ATS record in away games (1-3-0).
• The Eagles' winning percentage against the spread at home last year was .471 (8-9-0). Away, it was .300 (3-7-0).

Louisville vs. Boston College: Moneyline Betting Stats

• Louisville has been victorious in five of the seven contests it has been chosen as moneyline favorites in this season.
• The Cardinals have yet to play a game this season with better moneyline odds than -4545.
• Boston College has won one of the five games it was listed as the moneyline underdog this season (20%).
• The Eagles have not yet played a game with moneyline odds of +1600 or longer.
• Louisville has an implied victory probability of 97.8% according to the moneyline set by sportsbooks for this matchup.

Louisville vs. Boston College Head-to-Head Comparison

• Louisville has a +286 scoring differential, topping opponents by 19.1 points per game. It is putting up 89.2 points per game to rank 20th in college basketball and is giving up 70.1 per contest to rank 98th in college basketball.
• Ryan Conwell is 34th in college basketball with a team-high 19.9 points per game.
• Boston College outscores opponents by 2.1 points per game (posting 69.5 points per game, 316th in college basketball, and giving up 67.4 per contest, 52nd in college basketball) and has a +31 scoring differential.
• Boston College's leading scorer, Donald Hand Jr., ranks 235th in the nation, scoring 15.5 points per game.
• The 39.5 rebounds per game the Cardinals average rank 10th in the nation, and are 9.5 more than the 30 their opponents collect per contest.
• Sananda Fru tops the Cardinals with 6.7 rebounds per game (206th in college basketball play).
• The Eagles record 35.5 rebounds per game (74th in college basketball) while allowing 34 per contest to opponents. They outrebound opponents by 1.5 boards per game.
• Aidan Shaw's 7.2 rebounds per game lead the Eagles and rank 139th in the country.
• Louisville ranks 28th in college basketball by averaging 108 points per 100 possessions on offense, and defensively is 40th in college basketball, allowing 84.9 points per 100 possessions.
• The Eagles rank 322nd in college basketball averaging 89.6 points per 100 possessions on offense, and defensively are 65th, allowing 87 points per 100 possessions.

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