Lakers vs. Warriors Prediction, Odds, Picks, Best Bets for Oct. 21

Lakers vs. Warriors Game Info

• Date: Wednesday, October 21, 2026
• Time: 10 p.m. ET
• Venue: Crypto.com Arena -- Los Angeles, California
• Coverage: ESPN

The Los Angeles Lakers host the Golden State Warriors at Crypto.com Arena to start the 2026-27 season for both teams, with the game starting at 10 p.m. ET on Wednesday, October 21, 2026. The Lakers are 6.5-point favorites in the contest. The point total is 233.5 for the matchup.

Lakers vs. Warriors Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Lakers vs. Warriors Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction:

Lakers vs. Warriors Betting Trends

• The Lakers won 45 games against the spread last season, while failing to cover or pushing 37 times.
• Against the spread, as underdogs of 6.5 points or more, the Warriors went 7-10 last year.
• Last season, 43 Lakers games went over the point total.
• The Warriors had 49 of their 82 games go over the point total last year.
• Los Angeles did a better job covering the spread when playing at home (24-16-1) last season than it did in road games (21-20-0).
• Golden State had the same winning percentage against the spread (.415) at home (17-23-1 record) and on the road (17-24-0) last year.

Lakers Leaders

• Luka Doncic put up 33.5 points last year, plus 7.7 boards and 8.3 assists.
• Austin Reaves averaged 23.3 points, 4.7 rebounds and 5.5 assists. He made 49% of his shots from the field and 36% from 3-point range, with 2.3 triples per game.
• Quentin Grimes' numbers last season were 13.4 points, 3.6 boards and 3.3 assists per contest. He made 45% of his shots from the floor and 33.4% from 3-point range, with an average of 1.7 treys.
• Sandro Mamukelashvili put up 11.2 points, 4.9 rebounds and 1.9 assists. He made 52.3% of his shots from the field and 38.9% from 3-point range, with 1.4 treys per game.
• Collin Sexton put up 15.4 points, 2.3 boards and 3.3 assists. He sank 48.5% of his shots from the field and 40.1% from 3-point range, with 1.6 triples per contest.

Warriors Leaders

• Brandin Podziemski recorded 13.8 points, 3.7 assists and 5.1 boards last season.
• Stephen Curry averaged 26.6 points, 4.7 assists and 3.6 boards.
• Draymond Green averaged 8.4 points last season, plus 5.5 assists and 5.5 rebounds.
• Brandon Williams collected 13 points, 3.9 assists and 2.9 rebounds.
• Jimmy Butler III collected 20 points, 5.6 boards and 4.9 assists. Defensively, he put up 1.4 steals and 0.2 blocked shots.

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