Lakers vs. Clippers Prediction, Odds, Picks, Best Bets for Oct. 23

Lakers vs. Clippers Game Info

• Date: Friday, October 23, 2026
• Time: 10 p.m. ET
• Venue: Crypto.com Arena -- Los Angeles, California
• Coverage: Spectrum SportsNet, Spectrum SportsNet+, and ClipperVision

The Los Angeles Lakers (1-0) are at home in Pacific Division action against the Los Angeles Clippers (1-0) on Friday, October 23, 2026 at 10 p.m. ET. The Lakers are favored by 9.5 points in the game, the first matchup between the teams this season. The matchup's point total is set at 225.5.

Lakers vs. Clippers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Lakers vs. Clippers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Lakers win (60.9%)

Lakers vs. Clippers Betting Trends

• The Lakers compiled a 45-36-1 record against the spread last season.
• The Clippers had one win ATS (1-1) as underdogs of 9.5 points or more last season.
• Lakers games hit the over 43 out of 82 times last season.
• In 82 Clippers games last season, 43 of them went over the total.
• The Lakers owned a better record against the spread in home games (24-16-1) than they did in away games (21-20-0) last season.
• The Clippers performed better against the spread at home (22-19-0) than on the road (20-21-0) last year.

Lakers Leaders

• Luka Doncic put up 33.5 points, 7.7 boards and 8.3 assists last year. He also sank 47.6% of his shots from the field and 36.6% from beyond the arc, with 4 triples per game (first in NBA).
• Austin Reaves' numbers last season were 23.3 points, 4.7 rebounds and 5.5 assists per game. He made 49% of his shots from the floor and 36% from beyond the arc, with an average of 2.3 triples.
• Quentin Grimes' numbers last season were 13.4 points, 3.6 rebounds and 3.3 assists per contest. He drained 45% of his shots from the floor and 33.4% from 3-point range, with an average of 1.7 treys.
• Sandro Mamukelashvili's numbers last season were 11.2 points, 4.9 boards and 1.9 assists per game. He drained 52.3% of his shots from the field and 38.9% from beyond the arc, with an average of 1.4 treys.
• Collin Sexton posted 15.4 points, 2.3 rebounds and 3.3 assists per game, plus 1.1 steals and 0.1 blocks.

Clippers Leaders

• Brandon Ingram's numbers last season were 21.5 points, 5.6 boards and 3.7 assists per contest, shooting 47.7% from the field and 38.2% from beyond the arc, with an average of 1.8 made 3-pointers.
• Kris Dunn put up 7.3 points, 3.3 boards and 3.6 assists last season. At the other end, he delivered 1.6 steals (sixth in league) and 0.2 blocked shots.
• Darius Garland recorded 18.8 points last season, plus 6.7 assists and 2.4 rebounds.
• Brook Lopez averaged 8.5 points, 1.3 assists and 3.6 boards.
• Rui Hachimura averaged 11.5 points, 3.3 boards and 0.8 assists.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.