Kyren Williams Fantasy Football Week 1: Stats and Projections vs. 49ers

Kyren Williams and the Los Angeles Rams will meet the San Francisco 49ers -- whose run defense was ranked 11th in the league last year (107.8 yards allowed per game) -- in Week 1, on Thursday at 8:35 p.m. ET.

Thinking about Williams for your DFS roster, with his next game versus the 49ers? We've got stats and info for you in this article.

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Kyren Williams Week 1 Fantasy Football Projection

• Matchup: Los Angeles Rams vs. San Francisco 49ers
• Game Date: September 10, 2026
• Game Time: 8:35 p.m.
• Projected Fantasy Points: 10.3
• PPR Projected Fantasy Points: 10.9
• Projected Rushing Yards: 62.09
• Projected Rushing TDs: 0.48
• Projected Receiving Yards: 8.03
• Projected Receiving TDs: 0.08

Projections provided by numberFire

Williams 2025 Fantasy Performance

• Williams was eighth at his position, and 26th overall, with 227.3 fantasy points (13.4 per game) last season.
• Williams accumulated 23.7 fantasy points -- 21 carries, 87 yards, 2 TDs; 4 receptions, 30 yards -- in Week 2 versus the Chicago Bears, which was his best game last season.
• In Week 5 versus the San Francisco 49ers, Williams posted 23.1 fantasy points (his second-best total last year), via these numbers: 14 carries, 65 yards; 8 receptions, 66 yards, 2 TDs.
• In Week 12 versus the Tampa Bay Buccaneers, Williams posted a season-low 4.8 fantasy points, courtesy of these numbers: 12 carries, 46 yards.
• Williams collected 6.5 fantasy points -- 12 carries, 54 yards -- in his second-worst game of the season. That was in Week 7 versus the Jacksonville Jaguars.

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49ers Defensive Performance

• Last season, San Francisco allowed four quarterbacks to put up more than 300 passing yards in a game.
• The 49ers allowed at least one passing touchdown to 15 opposing QBs last season.
• Through the air last season, San Francisco gave up two or more touchdown passes to 10 opposing QBs.
• Last season, the 49ers allowed just three players to throw for at least three TDs in a game.
• Through the air, San Francisco allowed over 100 receiving yards to four players last season.
• The 49ers allowed 27 players to haul in a touchdown pass against them last season.
• Looking at pass defense, San Francisco allowed only two players to catch at least two touchdown passes against it last year.
• Looking at run defense, the 49ers allowed more than 100 rushing yards to just two players last season.
• In terms of run defense, San Francisco gave up at least one rushing touchdown to 11 players last season.
• The 49ers allowed at least two rushing TDs on the ground to only two players last season.

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