Kansas vs Oklahoma State Prediction, Odds, Picks, Best Bets for Week 10 2025

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Saturday's slate in college football includes a matchup between the Kansas Jayhawks and the Oklahoma State Cowboys.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Kansas vs Oklahoma State Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Kansas: (-3448) | Oklahoma State: (+1400)
Spread: Kansas: -24.5 (-110) | Oklahoma State: +24.5 (-110)
Total: 55.5 -- Over: (-105) | Under: (-115)

Against the spread, Kansas is 3-5-0 this season.
Kansas has no wins ATS (0-1) as a 24.5-point favorite or greater this year.
There have been four Kansas games (of eight) that went over the total this year.
Oklahoma State has one win against the spread this season.
Oklahoma State has no wins ATS (0-2) as a 24.5-point underdog or greater this season.
There have been four Oklahoma State games (out of eight) that went over the total this season.

All college football win probability predictions and picks are according to numberFire.
Prediction: Jayhawks win (92.5%)

Oklahoma State is the underdog by 24.5 points against Kansas. Oklahoma State is -110 to cover the spread, and Kansas is -110.

A total of 55.5 points has been set for the Kansas-Oklahoma State matchup on Nov. 1, with the over available at -105 and the under at -115.

The Kansas vs Oklahoma State moneyline has Kansas as a -3448 favorite, while Oklahoma State is a +1400 underdog.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Kansas	30.5	48	25.9	86	54.3	8
Oklahoma State	14.5	132	38.9	134	55.3	8

Check out even more in-depth Kansas vs. Oklahoma State analysis on FanDuel Research.

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