James Cook Fantasy Football Week 1: Stats and Projections vs. Texans

Buffalo Bills RB James Cook will take on the team with last season's fourth-ranked run defense, the Houston Texans (93.7 yards conceded per game), in Week 1 -- beginning at 1 p.m. ET on Sunday.

For more details on Cook, if you're considering him for your DFS lineup, check out this article before his upcoming matchup against the Texans.

Thinking about playing Cook this week? Start building your FanDuel fantasy football lineup today!

James Cook Week 1 Fantasy Football Projection

• Matchup: Buffalo Bills at Houston Texans
• Game Date: September 13, 2026
• Game Time: 1 p.m.
• Projected Fantasy Points: 15.0
• PPR Projected Fantasy Points: 16.2
• Projected Rushing Yards: 89.86
• Projected Rushing TDs: 0.62
• Projected Receiving Yards: 20.05
• Projected Receiving TDs: 0.12

Projections provided by numberFire

Cook 2025 Fantasy Performance

• In Week 8 last season against the Carolina Panthers, Cook posted a season-high of 33.6 fantasy points, with these numbers: 19 carries, 216 yards, 2 TDs.
• In Week 15 against the New England Patriots, Cook put up 29.1 fantasy points (his second-best total last season), via this stat line: 22 carries, 107 yards, 2 TDs; 2 receptions, 4 yards, 1 TD.
• In his worst game of the season, Cook ended up with 1.5 fantasy points -- 2 carries, 15 yards. That happened in Week 18 against the New York Jets.
• In his second-worst performance of the year -- Week 5 versus the New England Patriots -- Cook had 4.9 fantasy points. His stat line: 15 carries, 49 yards.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Texans Defensive Performance

• In last year's action, Houston did not allow a quarterback to put up more than 300 passing yards in a game.
• Last year, the Texans allowed 12 QBs to throw at least one touchdown pass in a game.
• Through the air last season, Houston allowed at least two passing touchdowns to seven opposing QBs.
• Last season, the Texans allowed only one player to throw for three or more TDs in a game.
• Houston let five players put up over 100 receiving yards in a game last year.
• Against the Texans last season, 18 players hauled in a TD pass.
• Looking at pass defense, Houston allowed only two players to catch at least two touchdown passes against it last year.
• In the run game, two players racked up more than 100 rushing yards in a game against the Texans last season.
• On the ground, Houston allowed 12 players to score at least one rushing touchdown against them last season.
• Only one player ran for multiple TDs in a game versus the Texans last year.

Want more data and analysis on James Cook? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.