The No. 2 Iowa State Cyclones (27-7) play the No. 15 South Dakota State Jackrabbits (22-12) in the opening round of the NCAA Tournament on Thursday, beginning at 7:35 PM ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. South Dakota State Game Info and Odds

• Game Day: Thursday, March 21, 2024
• Game Time: 7:35 PM ET
• TV Channel: truTV
• Location: Omaha, Nebraska
• Arena: CHI Health Center Omaha

See these betting trends and insights before you bet on Thursday's Iowa State-South Dakota State spread (Iowa State -15.5) or total (135.5 points).

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Iowa State vs. South Dakota State: ATS Betting Stats and Trends

• Iowa State has put together a 24-10-0 ATS record so far this year.
• South Dakota State has compiled a 16-15-0 record against the spread this year.
• Against the spread, the Cyclones have performed better when playing at home, covering 14 times in 18 home games, and seven times in 10 road games.
• In 2023-24 against the spread, the Jackrabbits have a lower winning percentage at home (.364, 4-7-0 record) than away (.636, 7-4-0).

Iowa State vs. South Dakota State: Moneyline Betting Stats

• Iowa State has been the moneyline favorite in 23 games this season and has come away with the win 20 times (87%) in those contests.
• The Cyclones have yet to lose in seven games when named as moneyline favorite of -2100 or better.
• South Dakota State has won 50% of the games this season it was the underdog on the moneyline (3-3).
• The Jackrabbits have never played a game this season with moneyline odds of +1000 or longer.
• Iowa State has an implied victory probability of 95.5% according to the moneyline set for this matchup.

Iowa State vs. South Dakota State Head-to-Head Comparison

• Iowa State outscores opponents by 14.3 points per game (scoring 75.6 per game to rank 113th in college basketball while allowing 61.3 per contest to rank fourth in college basketball) and has a +485 scoring differential overall.
• Keshon Gilbert's 13.8 points per game lead Iowa State and are 419th in the nation.
• South Dakota State's +202 scoring differential (outscoring opponents by six points per game) is a result of putting up 76.8 points per game (87th in college basketball) while allowing 70.8 per outing (140th in college basketball).
• Zeke Mayo is ranked 58th in the country with a team-leading 18.8 points per game.
• The Cyclones record 34 rebounds per game (260th in college basketball) compared to the 33.1 of their opponents.
• Tre King leads the Cyclones with 5.2 rebounds per game (542nd in college basketball play).
• The 35.8 rebounds per game the Jackrabbits accumulate rank 144th in college basketball, two more than the 33.8 their opponents record.
• William Kyle III averages 6.6 rebounds per game (228th in college basketball) to lead the Jackrabbits.
• Iowa State ranks 81st in college basketball by averaging 99 points per 100 possessions on offense, and defensively is second in college basketball, allowing 80.3 points per 100 possessions.
• The Jackrabbits rank 51st in college basketball with 100.9 points scored per 100 possessions, and 187th defensively with 93.1 points conceded per 100 possessions.

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