Houston vs Florida State College Basketball Prediction, Odds, Picks, Best Bets for Dec. 6

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The Florida State Seminoles (5-3) battle the Houston Cougars (7-1) at Toyota Center on December 6, 2025.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Houston vs. Florida State Game Info and Odds

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Houston win (84.2%)

See these betting insights and trends before you bet on Saturday's Houston-Florida State spread (Houston -14.5) or over/under (147.5 points).

Houston has won just two games against the spread this season.
Florida State has put together a 5-3-0 ATS record so far this season.
As a 14.5-point underdog or more in 2025-26, Florida State is 1-0 against the spread compared to the 2-3 ATS record Houston puts up as a 14.5-point favorite.
The Cougars covered the spread in a lower percentage of their home games than away games last season. They covered 10 times in 17 games at home, and they covered seven times in 10 games on the road.
The Seminoles were better against the spread at home (10-6-0) than away (4-7-0) last year.

Houston has come away with four wins in the five contests it has been listed as the moneyline favorite in this season.
The Cougars have been listed as a favorite of -1250 or more on two occasions this season and won both games.
Florida State has been the moneyline underdog just one other time so far this season, a game it lost.
The Seminoles have played as a moneyline underdog of +740 or longer in only one game this season, which they lost.
The moneyline set for this matchup implies Houston has a 92.6% chance of walking away with the win.

Offensively, Houston was the 182nd-ranked team in college basketball (73.7 points per game) last year. Defensively, it was best (58.7 points conceded per game).
Last year, Houston was 96th in the country in rebounds (33.3 per game) and 10th-best in rebounds conceded (26.9).
At 12.0 assists per game last season, Houston was 292nd in college basketball.
In terms of turnovers, Houston was third-best in the nation in committing them (8.4 per game) last year. It was 85th in forcing them (12.3 per game).
Last season Florida State averaged 74.5 points per game (153rd-ranked in college basketball) and surrendered 72.5 points per contest (195th-ranked).
Florida State grabbed 31.3 boards per game (214th-ranked in college basketball) last season, while allowing 31.8 rebounds per contest (217th-ranked).
Florida State ranked 219th in college basketball with 13.0 assists per contest.
Florida State averaged 12.2 turnovers per game (277th-ranked in college basketball). It forced 13.0 turnovers per contest (50th-ranked).

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