Guardians vs Blue Jays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 1

Odds updated as of 6:12 p.m.

The MLB slate on Tuesday includes the Cleveland Guardians facing the Toronto Blue Jays.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Blue Jays Game Info

• Cleveland Guardians (69-68) vs. Toronto Blue Jays (68-70)
• Date: Tuesday, September 1, 2026
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and SNET

Guardians vs Blue Jays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-184) | TOR: (+154)
• Spread: CLE: -1.5 (+122) | TOR: +1.5 (-146)
• Total: 7.5 -- Over: (-124) | Under: (+102)

Guardians vs Blue Jays Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 12-7, 3.98 ERA vs Spencer Miles (Blue Jays) - 5-2, 2.92 ERA

This contest's pitching matchup is set, as the Guardians will send Gavin Williams (12-7) to the mound, while Spencer Miles (5-2) will take the ball for the Blue Jays. Williams and his team have a record of 13-13-0 against the spread when he starts. Williams' team is 12-9 this season when he starts and they are the moneyline favorite. When Miles starts, the Blue Jays have gone 2-3-0 against the spread. The Blue Jays were the underdog on the moneyline for two Miles starts this season -- they lost both.

Guardians vs Blue Jays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (55.5%)

Guardians vs Blue Jays Moneyline

• Toronto is a +154 underdog on the moneyline, while Cleveland is a -184 favorite at home.

Guardians vs Blue Jays Spread

• The Blue Jays are at the Guardians, and are +1.5 on the runline. The Blue Jays are +122 to cover the spread, and the Guardians are -146.

Guardians vs Blue Jays Over/Under

• Guardians versus Blue Jays, on Sept. 1, has an over/under of 7.5, with the over being -124 and the under +102.

Bet on Cleveland Guardians vs. Toronto Blue Jays on FanDuel today!

Guardians vs Blue Jays Betting Trends

• The Guardians have been victorious in 40, or 50.6%, of the 79 contests they have been chosen as favorites in this season.
• This year Cleveland has won three of four games when listed as at least -184 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 63 of their 131 opportunities.
• The Guardians have an against the spread mark of 63-68-0 in 131 games with a line this season.
• The Blue Jays have compiled a 27-37 record in games they were the underdog on the moneyline (winning 42.2% of those games).
• Toronto is 3-3 (winning 50% of its games) when it has played as a moneyline underdog of +154 or longer.
• The Blue Jays have played in 134 games with an over/under set, and have combined with their opponents to go over the total 68 times (68-64-2).
• The Blue Jays have a 66-68-0 record against the spread this season.

Guardians Player Leaders

• Chase DeLauter leads Cleveland in slugging percentage (.454) and total hits (125) this season. He's batting .293 with an on-base percentage of .365.
• Among qualifying batters in the majors, he ranks 10th in batting average, 25th in on-base percentage, and 42nd in slugging.
• Jose Ramirez is batting .243 with 24 doubles, 11 home runs and 56 walks, while slugging .393 with an on-base percentage of .339.
• Among qualifiers, he is 93rd in batting average, 58th in on-base percentage and 99th in slugging percentage.
• Ramirez has picked up a hit in two games in a row. In his last five games he is batting .381 with four doubles, a home run, two walks and nine RBIs.
• Steven Kwan leads Cleveland with an OBP of .377 this season while batting .275 with 71 walks and 68 runs scored.
• Kwan brings a two-game hitting streak into this game. In his last five games he is hitting .476 with two doubles, two walks and two RBIs.
• Brayan Rocchio has been key for Cleveland with 114 hits, an OBP of .307 plus a slugging percentage of .363.

Blue Jays Player Leaders

• Ernie Clement has a .390 slugging percentage, which leads the Blue Jays. He's batting .276 with an on-base percentage of .301.
• Including all qualifying hitters, he is 32nd in batting average, while his on-base percentage is 117th and he is 104th in slugging.
• Vladimir Guerrero Jr. has a .331 on-base percentage to lead his team. He has a batting average of .258 while slugging .348.
• Including all qualified players, he ranks 63rd in batting average, 68th in on-base percentage and 133rd in slugging percentage.
• Kazuma Okamoto has put up 111 hits, a team-best for the Blue Jays.
• George Springer has 19 doubles, two triples, 14 home runs and 42 walks while hitting .254.

Guardians vs Blue Jays Head to Head

• 4/26/2026: 4-2 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/25/2026: 5-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 7, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/24/2026: 8-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/26/2025: 6-0 TOR (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/25/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/24/2025: 10-6 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/4/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/3/2025: 5-3 CLE (Favorite: Blue Jays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/2/2025: 5-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/23/2024: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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