Giants vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 3:12 p.m.

The Sunday schedule in MLB includes a matchup between the San Francisco Giants and the Chicago White Sox.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Giants vs White Sox Game Info

• San Francisco Giants (21-31) vs. Chicago White Sox (26-25)
• Date: Sunday, May 24, 2026
• Time: 4:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and CHSN

Giants vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-124) | CHW: (+106)
• Spread: SF: -1.5 (+176) | CHW: +1.5 (-215)
• Total: 8 -- Over: (-105) | Under: (-115)

Giants vs White Sox Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Giants) - 3-6, 4.28 ERA vs Noah Schultz (White Sox) - 2-3, 4.93 ERA

The Giants will call on Robbie Ray (3-6) against the White Sox and Noah Schultz (2-3). When Ray starts, his team is 4-6-0 against the spread this season. Ray's team is 1-1 this season when he starts and they're favored on the moneyline. The White Sox have gone 3-4-0 ATS in Schultz's seven starts that had a set spread. The White Sox have a 3-2 record in Schultz's five starts this season when they were the underdog on the moneyline.

Giants vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (54.9%)

Giants vs White Sox Moneyline

• Chicago is the underdog, +106 on the moneyline, while San Francisco is a -124 favorite at home.

Giants vs White Sox Spread

• The Giants are hosting the White Sox and are favored by 1.5 runs on the spread. The Giants are +176 to cover the runline, with the White Sox being -215.

Giants vs White Sox Over/Under

• A combined run total of 8 has been set for Giants-White Sox on May 24, with the over at -105 and the under at -115.

Bet on San Francisco Giants vs. Chicago White Sox on FanDuel today!

Giants vs White Sox Betting Trends

• The Giants have won in seven, or 50%, of the 14 contests they have been named as odds-on favorites in this year.
• This season San Francisco has been victorious four times in six chances when named as a favorite of at least -124 on the moneyline.
• The Giants and their opponents have gone over the total this season in 24 of their 52 opportunities.
• The Giants are 21-31-0 against the spread in their 52 games with a line set by sportsbooks this season.
• The White Sox have gone 21-22 in games they were listed as the moneyline underdog (winning 48.8% of those games).
• Chicago has an 18-19 record (winning 48.6% of its games) when playing as a moneyline underdog of +106 or longer.
• The White Sox have played in 49 games with a set over/under, and have combined with opponents to go over the total 28 times (28-21-0).
• The White Sox have covered 59.2% of their games this season, going 29-20-0 ATS.

Giants Player Leaders

• Luis Arraez leads San Francisco with an OBP of .360, plus a team-best slugging percentage of .431. He's batting .323 on the season.
• Among qualifying batters in baseball, his batting average ranks third, his on-base percentage ranks 40th, and he is 69th in slugging.
• Arraez has recorded at least one hit in four straight games. In his last five games he is hitting .286 with a triple and two RBIs.
• Casey Schmitt leads San Francisco with 48 hits. He is batting .291 this season and has 19 extra-base hits. He's also slugging .533 with an on-base percentage of .331.
• His batting average ranks 24th among qualified players, his on-base percentage 81st, and his slugging percentage 15th.
• Matt Chapman has collected 45 base hits, an OBP of .313 and a slugging percentage of .328 this season.
• Chapman has logged a hit or more in four games in a row. In his last five games he is batting .353 with two doubles and three walks.
• Willy Adames is batting .233 with a .269 OBP and 17 RBI for San Francisco this season.
• Adames brings a two-game hitting streak into this game. In his last five games he is hitting .222 with three home runs, two walks and four RBIs.

White Sox Player Leaders

• Miguel Vargas is batting .243 with eight doubles, a triple, 11 home runs and 32 walks. He's slugging .486 with an on-base percentage of .370.
• He ranks 98th in batting average, 30th in on-base percentage and 33rd in slugging percentage among all qualified batters in the big leagues.
• Munetaka Murakami leads his team with 43 hits and a .380 OBP. He has a batting average of .240 while slugging .542.
• Including all qualifying hitters, he is 102nd in batting average, 21st in on-base percentage and 14th in slugging percentage.
• Colson Montgomery is batting .223 with eight doubles, 13 home runs and 19 walks.
• Chase Meidroth's .363 slugging percentage paces his team.

Giants vs White Sox Head to Head

• 5/23/2026: 10-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/22/2026: 9-4 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/29/2025: 5-2 CHW (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/28/2025: 1-0 CHW (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 6/27/2025: 3-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/21/2024: 6-2 CHW (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/20/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 8/19/2024: 5-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/6/2023: 16-6 SF (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/5/2023: 7-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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