Florida vs Ole Miss Prediction, Odds, Picks, Best Bets for Week 4 2026

Saturday's slate in college football includes a matchup between the Florida Gators and the Ole Miss Rebels.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Florida vs Ole Miss Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Florida: (-184) | Ole Miss: (+152)
• Spread: Florida: -3.5 (-110) | Ole Miss: +3.5 (-110)
• Total: 59.5 -- Over: (-105) | Under: (-115)

Florida vs Ole Miss Betting Trends

• Florida has won twice against the spread this year.
• As a 3.5-point or greater favorite, Florida has one win ATS (1-1) this season.
• Two of three Florida games have hit the over this season.
• Ole Miss has one win against the spread this season.
• One of Ole Miss' three games has gone over the point total.

Florida vs Ole Miss Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (50.2%)

Florida vs Ole Miss Point Spread

Florida is a 3.5-point favorite against Ole Miss. Florida is -110 to cover the spread, and Ole Miss is -110.

Florida vs Ole Miss Over/Under

A combined point total of 59.5 has been set for Florida-Ole Miss on Sept. 26, with the over at -105 and the under at -115.

Florida vs Ole Miss Moneyline

Ole Miss is a +152 underdog on the moneyline, while Florida is a -184 favorite.

Florida vs. Ole Miss Points Insights

Florida vs. Ole Miss Game Info

• Game day: Saturday, September 26, 2026
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Gainesville, Florida
• Stadium: Ben Hill Griffin Stadium

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Check out even more in-depth Florida vs. Ole Miss analysis on FanDuel Research.