Florida vs Oklahoma Prediction, Odds, Picks, Best Bets for Week 10 2026

The Saturday slate in college football includes a matchup between the Florida Gators and the Oklahoma Sooners.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

Florida vs Oklahoma Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Florida: (-220) | Oklahoma: (+184)
• Spread: Florida: -5.5 (-118) | Oklahoma: +5.5 (-104)
• Total: 44.5 -- Over: (-118) | Under: (-104)

Florida vs Oklahoma Betting Trends

• Florida has beaten the spread four times in eight games.
• As a 5.5-point or greater favorite, Florida has one win ATS (1-2) this season.
• There have been five Florida games (of eight) that hit the over this season.
• Oklahoma's record against the spread in 2026 is 3-5-0.
• Oklahoma has won once ATS (1-1) as a 5.5-point underdog or more this year.
• Oklahoma has seen four of its eight games hit the over.

Florida vs Oklahoma Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Gators win (71.7%)

Florida vs Oklahoma Point Spread

Florida is a 5.5-point favorite against Oklahoma. Florida is -118 to cover the spread, and Oklahoma is -104.

Florida vs Oklahoma Over/Under

Florida versus Oklahoma on Nov. 7 has an over/under of 44.5 points, with the over -118 and the under -104.

Florida vs Oklahoma Moneyline

Looking at the moneyline for Florida-Oklahoma, Florida is the favorite at -220, and Oklahoma is +184.

Florida vs. Oklahoma Points Insights

Florida vs. Oklahoma Game Info

• Game day: Saturday, November 7, 2026
• Game time: 7:45 p.m. ET
• TV channel: SEC Network
• Location: Gainesville, Florida
• Stadium: Ben Hill Griffin Stadium

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Check out even more in-depth Florida vs. Oklahoma analysis on FanDuel Research.