Falcons vs Colts Prediction Today - NFL Preseason Picks, Odds & Best Bets Saturday

NFL Betting Picks in Summary

• Colts -3.5
• Cooper Rush 20+ Passing Yards
• Under 36.5

Atlanta and Indianapolis meet Saturday afternoon, and the Falcons appear to be rotating even further down their quarterback depth chart than they did a week ago.

All NFL preseason odds come from FanDuel Sportsbook's NFL betting odds and may change after this article is published.

Depth Chart Notes

Atlanta: Cooper Rush has the only live prop on this board. Rush sits behind both Michael Penix Jr. (still working back from ACL surgery) and Tua Tagovailoa, who started last week's game in Denver — this points to Atlanta getting Rush extended work this time rather than Tua again.

Indianapolis: No Colts player has a posted prop for this game. Anthony Richardson started and played a full half against Carolina last week, so his lack of a market here is worth confirming before kickoff.

NFL Predictions and Picks for Preseason Week 2

Atlanta Falcons at Indianapolis Colts (Sat, 1 p.m. ET)

Colts -3.5 (-114)

Richardson and Riley Leonard both showed well in an extended look last week, giving Indianapolis a real, established quarterback plan. Atlanta turning to its third option behind Rush suggests a lesser degree of quarterback continuity on the other side.

Cooper Rush 20+ Passing Yards (+168)

Rush is a veteran journeyman with real NFL starting experience of his own, and a plus-money price on a modest 20-yard floor looks fair given the only live market on this entire board belongs to him.

Under 36.5 (-118)

With Atlanta's only confirmed passer sitting behind two other quarterbacks on the depth chart and Indianapolis's own market strangely quiet, this looks like a game with more uncertainty than rhythm on both sides.