East Carolina vs Memphis Prediction, Odds, Picks, Best Bets for Week 12 2025

The college football slate on Saturday includes the East Carolina Pirates taking on the Memphis Tigers.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

East Carolina vs Memphis Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: East Carolina: (-152) | Memphis: (+128)
• Spread: East Carolina: -3.5 (-102) | Memphis: +3.5 (-120)
• Total: 58.5 -- Over: (-108) | Under: (-112)

East Carolina vs Memphis Betting Trends

• East Carolina has five wins in nine games against the spread this year.
• East Carolina's ATS record as 3.5-point or bigger favorites is 4-2.
• There have been four East Carolina games (of nine) that went over the total this season.
• Memphis has covered the spread eight times in 10 games.
• Memphis has covered every time (2-0) as a 3.5-point or greater underdog this year.
• There have been five Memphis games (out of 10) that hit the over this year.

East Carolina vs Memphis Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Pirates win (64%)

East Carolina vs Memphis Point Spread

Memphis is the underdog by 3.5 points against East Carolina. Memphis is -102 to cover the spread, and East Carolina is -120.

East Carolina vs Memphis Over/Under

A combined point total of 58.5 has been set for East Carolina-Memphis on Nov. 15, with the over at -108 and the under at -112.

East Carolina vs Memphis Moneyline

The moneyline numbers for East Carolina vs. Memphis reveal East Carolina as the favorite (-152) and Memphis as the underdog (+128).

East Carolina vs. Memphis Points Insights

East Carolina vs. Memphis Game Info

• Game day: Saturday, November 15, 2025
• Game time: 4 p.m. ET
• TV channel: ESPNU
• Location: Greenville, North Carolina
• Stadium: Bagwell Field at Dowdy-Ficklen Stadium

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Check out even more in-depth East Carolina vs. Memphis analysis on FanDuel Research.