Duke vs Stanford Prediction, Odds, Picks, Best Bets for Week 3 2026

The Duke Blue Devils will face the Stanford Cardinal in college football action on Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

Duke vs Stanford Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Duke: (-385) | Stanford: (+300)
• Spread: Duke: -10.5 (-104) | Stanford: +10.5 (-118)
• Total: 51.5 -- Over: (-104) | Under: (-118)

Duke vs Stanford Betting Trends

• Duke has posted two wins against the spread this year.
• Duke has had one game (of two) go over the total this year.
• Stanford has posted one win against the spread this year.
• Stanford is winless ATS (0-1) when playing as at least 10.5-point underdogs this year.
• Stanford and its opponent have yet to finish under the total this year.

Duke vs Stanford Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Blue Devils win (87.6%)

Duke vs Stanford Point Spread

Duke is a 10.5-point favorite against Stanford. Duke is -104 to cover the spread, and Stanford is -118.

Duke vs Stanford Over/Under

Duke versus Stanford, on Sept. 19, has an over/under of 51.5, with the over being -104 and the under -118.

Duke vs Stanford Moneyline

Stanford is a +300 underdog on the moneyline, while Duke is a -385 favorite.

Duke vs. Stanford Points Insights

Duke vs. Stanford Game Info

• Game day: Saturday, September 19, 2026
• Game time: 4 p.m. ET
• TV channel: The CW
• Location: Wilmington, North Carolina
• Stadium: Brooks Field at Wallace Wade Stadium

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Check out even more in-depth Duke vs. Stanford analysis on FanDuel Research.