Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 10:11 p.m.

Friday's slate in the MLB includes a matchup between the Los Angeles Dodgers and the San Francisco Giants.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (93-60) vs. San Francisco Giants (64-89)
• Date: Friday, September 18, 2026
• Time: 10:15 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: Apple TV+

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-320) | SF: (+260)
• Spread: LAD: -1.5 (-144) | SF: +1.5 (+120)
• Total: 8.5 -- Over: (+106) | Under: (-130)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Tyler Glasnow (Dodgers) - 4-1, 3.50 ERA vs César Perdomo (Giants) - 0-1, 3.68 ERA

The Dodgers will give the nod to Tyler Glasnow (4-1, 3.50 ERA), who is eyeing win No. 5 on the season, and the Giants will turn to Cesar Perdomo (0-1, 3.68 ERA). Glasnow's team is 4-6-0 against the spread this season in his starts. When Glasnow starts a game and his team is the favorite on the moneyline, they have a record of 7-3. Perdomo has started two games with set spreads, and the Giants went 1-1-0. The Giants were the moneyline underdog for two Perdomo starts this season -- they lost both.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (68.6%)

Dodgers vs Giants Moneyline

• Los Angeles is the favorite, -320 on the moneyline, while San Francisco is a +260 underdog on the road.

Dodgers vs Giants Spread

• The Giants are at the Dodgers, and are +1.5 on the runline. The Giants are -144 to cover the spread, and the Dodgers are +120.

Dodgers vs Giants Over/Under

• A combined run total of 8.5 has been set for Dodgers-Giants on Sept. 18, with the over at +106 and the under at -130.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have come away with 90 wins in the 145 contests they have been listed as the favorites in this season.
• Los Angeles has been a -320 moneyline favorite on five occasions this season and won every time.
• The Dodgers' games have gone over the total in 71 of their 151 opportunities.
• The Dodgers have an against the spread record of 62-89-0 in 151 games with a line this season.
• The Giants have won 39 of the 104 games they were listed as the moneyline underdog this season (37.5%).
• San Francisco has yet to play a game with moneyline odds of +260 or longer.
• The Giants have played in 150 games with a set over/under, and have combined with opponents to go over the total 74 times (74-66-10).
• The Giants are 73-77-0 ATS this season.

Dodgers Player Leaders

• Freddie Freeman leads Los Angeles in slugging percentage (.445) thanks to 49 extra-base hits. He has a .295 batting average and an on-base percentage of .372.
• Among qualified hitters, he ranks eighth in batting average, his on-base percentage ranks 14th, and he is 49th in slugging.
• Kyle Tucker is hitting .232 with 23 doubles, four triples, 16 home runs and 75 walks, while slugging .387 with an on-base percentage of .331.
• Among qualified batters, he ranks 110th in batting average, 67th in on-base percentage and 104th in slugging percentage.
• Tucker heads into this game looking to extend his two-game hit streak. In his last five games he is batting .353 with two doubles, two home runs, five walks and four RBIs.
• Max Muncy has 116 hits this season and has a slash line of .252/.350/.490.
• Mookie Betts has 20 home runs, 62 RBI and a batting average of .250 this season.

Giants Player Leaders

• Jung Hoo Lee has a team-high .397 slugging percentage. He's batting .274 with an on-base percentage of .317.
• Including all qualifying hitters in the big leagues, he is 36th in batting average, 90th in on-base percentage and 90th in slugging percentage.
• Bryce Eldridge is batting .269 with 23 doubles, 17 home runs and 59 walks. He's slugging .461 with an on-base percentage of .364.
• Drew Gilbert is hitting .233 with 14 doubles, three triples, 10 home runs and 36 walks.
• Christian Koss is batting .240 with five doubles, four home runs and nine walks.

Dodgers vs Giants Head to Head

• 5/14/2026: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/13/2026: 4-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/12/2026: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/11/2026: 9-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/23/2026: 3-0 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/22/2026: 3-0 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/21/2026: 3-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -186, Underdog Moneyline: +144)
• 9/21/2025: 3-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/20/2025: 7-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 9/19/2025: 6-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)

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