Cubs vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 10:12 p.m.

The Sunday schedule in MLB includes a matchup between the Chicago Cubs and the Miami Marlins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Cubs vs Marlins Game Info

• Chicago Cubs (81-62) vs. Miami Marlins (71-72)
• Date: Sunday, September 6, 2026
• Time: 1:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: Marlins.TV and MARQ

Cubs vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-144) | MIA: (+122)
• Spread: CHC: -1.5 (+118) | MIA: +1.5 (-142)
• Total: 8 -- Over: (-110) | Under: (-110)

Cubs vs Marlins Probable Starting Pitchers

Probable Pitchers: Clay Holmes (Cubs) - 6-6, 2.09 ERA vs Tyler Phillips (Marlins) - 4-6, 3.43 ERA

The Cubs will give the nod to Clay Holmes (6-6) against the Marlins and Tyler Phillips (4-6). Holmes' team is 6-8-0 against the spread this season in his starts. Holmes' team has been victorious in 55.6% of the games he's started as the moneyline favorite with a record of 5-4. When Phillips starts, the Marlins are 8-8-0 against the spread. The Marlins are 5-6 in Phillips' 11 starts this season that they were the underdog on the moneyline.

Cubs vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (56.2%)

Cubs vs Marlins Moneyline

• Chicago is a -144 favorite on the moneyline, while Miami is a +122 underdog at home.

Cubs vs Marlins Spread

• The Cubs are 1.5-run road favorites on the runline against the Marlins. The Cubs are +118 to cover, and the Marlins are -142.

Cubs vs Marlins Over/Under

• The over/under for Cubs-Marlins on Sept. 6 is 8. The over is -110, and the under is -110.

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Cubs vs Marlins Betting Trends

• The Cubs have been victorious in 53, or 57%, of the 93 contests they have been chosen as favorites in this season.
• This season Chicago has come away with a win 29 times in 47 chances when named as a favorite of at least -144 on the moneyline.
• The Cubs and their opponents have gone over the total this season in 77 of their 138 opportunities.
• The Cubs have an against the spread mark of 67-71-0 in 138 games with a line this season.
• The Marlins have a 30-48 record in games they were listed as the moneyline underdog (winning 38.5% of those games).
• Miami has a 7-19 record (winning only 26.9% of its games) when it has played as a moneyline underdog of +122 or longer.
• The Marlins have combined with opponents to go over the total 69 times this season for a 69-70-2 record against the over/under.
• The Marlins have a 72-69-0 record ATS this season (covering 51.1% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong leads Chicago in OBP (.375), slugging percentage (.568) and total hits (154) this season. He has a .279 batting average.
• Among the qualifying hitters in baseball, his batting average ranks 25th, his on-base percentage ranks 10th, and he is second in slugging.
• Crow-Armstrong will look for his fifth straight game with a hit in this contest. In his last five games he is batting .211 with a double, a home run, four walks and three RBIs.
• Alex Bregman has 28 doubles, a triple, 24 home runs and 68 walks. He's batting .260 and slugging .443 with an on-base percentage of .348.
• Among qualifiers, he ranks 62nd in batting average, 43rd in on-base percentage and 50th in slugging percentage.
• Seiya Suzuki has 129 hits this season and has a slash line of .270/.368/.480.
• Nico Hoerner has been key for Chicago with 148 hits, an OBP of .320 plus a slugging percentage of .362.
• Hoerner brings a two-game hitting streak into this game. In his last five games he is hitting .350 with two RBIs.

Marlins Player Leaders

• Otto Lopez has racked up a slugging percentage of .439, a team-best for the Marlins. He's batting .300 with an on-base percentage of .338.
• Including all the qualified hitters in the big leagues, his batting average is seventh, his on-base percentage ranks 56th, and he is 54th in slugging.
• Javier Sanoja is batting .286 with 29 doubles, two triples, seven home runs and 23 walks. He's slugging .427 with an on-base percentage of .326.
• Jakob Marsee is hitting .208 with 17 doubles, five triples, nine home runs and 71 walks.
• Heriberto Hernandez is batting .227 with 16 doubles, a triple, 23 home runs and 42 walks.

Cubs vs Marlins Head to Head

• 9/5/2026: 6-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/4/2026: 6-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/21/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/20/2025: 14-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/19/2025: 8-7 MIA (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/14/2025: 3-1 MIA (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/13/2025: 5-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/12/2025: 5-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 8/25/2024: 7-2 MIA (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 8/24/2024: 14-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)

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