College Football Predictions Tonight With 4 Best Bets, Prediction, Picks, and Odds

College Football Tonight: Best Bets and Predictions in Summary

• FIU -10.5
• South Alabama -2.5
• Over 66.5 (South Alabama vs Marshall)
• Missouri State +2.5

Tonight's college football slate features three matchups, and a look at how the market has priced each line turns up some real value — a double-digit favorite available at a real discount, and one of the highest totals of the night.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

Best Bets for Tonight's College Football Slate

Middle Tennessee at FIU (7:00 p.m. ET)

FIU -10.5 (-102)

A real, genuine discount for a double-digit favorite — Middle Tennessee getting the points actually costs more at -120, an 18-cent gap favoring the home side.

Prediction: FIU covers at home behind a real advantage on both sides of the ball against a struggling Middle Tennessee team.

Missouri State at Delaware (7:00 p.m. ET)

Missouri State +2.5 (-104)

A real, genuinely close number — Delaware laying the points costs 14 cents more at -118, a fair signal this one is close to a true coin flip.

Prediction: A tight game that could come down to the final possessions, with Missouri State's plus-money underdog price offering real value getting a field goal and change.

South Alabama at Marshall (7:30 p.m. ET)

South Alabama -2.5 (-105)

A real, modest road favorite in a genuinely close Sun Belt matchup, with pricing on both sides staying nearly even across the board.

Over 66.5 (-105)

Comfortably the highest total on tonight's board, and the over is priced 10 cents cheaper than the under — a real sign the market expects a genuine shootout.

Prediction: South Alabama escapes with a narrow road win while both offenses trade scores, pushing this one well past the total.