College Football Predictions & Picks: 7 Best Bets for Saturday's Noon Kickoff Window

College Football Betting Picks in Summary

• Ohio State -49.5
• Indiana -40.5
• Alabama -28.5
• Houston -20.5
• James Madison -6.5
• Bowling Green -2.5
• South Carolina -36.5

Fourteen games kick off the noon window Saturday, and this slate runs the full range — from a genuine coin-flip in Ohio to a handful of the widest spreads you'll see anywhere in college football this season.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

College Football Predictions and Picks

Ball State at Ohio State (Sat, 12:30 p.m. ET)

Ohio State -49.5 (-115)

The widest spread on the entire slate. No two-way moneyline is even posted for this one — a real sign of just how one-sided the market considers this matchup.

North Texas at Indiana (Sat, 12:00 p.m. ET)

Indiana -40.5 (-110)

Ranked No. 6 nationally and hosting, Indiana's spread here is genuinely rare territory — no moneyline is posted, consistent with a market that considers this close to a foregone conclusion.

East Carolina at Alabama (Sat, 12:00 p.m. ET)

Alabama -28.5 (+100)

A -7000 moneyline against a real, ranked-caliber SEC roster is about as clean a favorite as this slate offers.

Oregon State at Houston (Sat, 12:00 p.m. ET)

Houston -20.5 (-118)

Ranked No. 23, Houston is priced at -1800 at home against a rebuilding Oregon State roster — a real, well-supported gap on paper.

Liberty at James Madison (Sat, 12:00 p.m. ET)

James Madison -6.5 (-105)

A genuinely moderate number by comparison to the rest of this slate — James Madison is favored at home in a much more competitive Group of Five matchup than most of the games kicking off at noon.

Tarleton State at Bowling Green (Sat, 12:00 p.m. ET)

Bowling Green -2.5 (-110)

The lone true coin flip on this entire slate. A modest home number at -134 on the moneyline is a fair, defensible lean without needing a blowout to be right.

Kent State at South Carolina (Sat, 12:45 p.m. ET)

South Carolina -36.5 (-105)

Another game with no moneyline posted at all — a clear signal of just how lopsided South Carolina's SEC roster is expected to be against this opponent at home.