A matchup between No. 13 Alabama and No. 24 Florida at 7:00 PM ET is one of the highlights of Wednesday's slate, which includes seven games involving teams ranked in the AP Poll's Top 25. For picks and predictions for each contest, continue reading.

With Wednesday's college basketball upon us, stay on top of the most current betting trends with our preview below.

Penn State vs. Illinois

• Matchup: No. 12 Illinois Fighting Illini at Penn State Nittany Lions
• Projected Winner: Illinois (75.47% win probability)
• Spread: Illinois (-7.5)
• Time: 6:30 PM ET
• Date: February 21
• TV Channel: BTN

Bet on Penn State vs. Illinois with FanDuel Sportsbook.

Alabama vs. Florida

• Matchup: No. 24 Florida Gators at No. 13 Alabama Crimson Tide
• Projected Winner: Alabama (72.18% win probability)
• Spread: Alabama (-10.5)
• Time: 7:00 PM ET
• Date: February 22
• TV Channel: ESPN2

Bet on Alabama vs. Florida with FanDuel Sportsbook.

George Mason vs. Dayton

• Matchup: No. 16 Dayton Flyers at George Mason Patriots
• Projected Winner: Dayton (51.92% win probability)
• Spread: Dayton (-3.5)
• Time: 7:00 PM ET
• Date: February 22
• TV Channel: ESPN+

Bet on George Mason vs. Dayton with FanDuel Sportsbook.

Miami (FL) vs. Duke

• Matchup: No. 8 Duke Blue Devils at Miami Hurricanes
• Projected Winner: Duke (64.71% win probability)
• Spread: Duke (-6.5)
• Time: 7:00 PM ET
• Date: February 22
• TV Channel: ESPN

Bet on Miami (FL) vs. Duke with FanDuel Sportsbook.

LSU vs. Kentucky

• Matchup: No. 17 Kentucky Wildcats at LSU Tigers
• Projected Winner: Kentucky (62.57% win probability)
• Spread: Kentucky (-5.5)
• Time: 9:00 PM ET
• Date: February 22
• TV Channel: ESPN

Bet on LSU vs. Kentucky with FanDuel Sportsbook.

Marquette vs. DePaul

• Matchup: DePaul Blue Demons at No. 7 Marquette Golden Eagles
• Projected Winner: Marquette (99.27% win probability)
• Spread: Marquette (-27.5)
• Time: 9:00 PM ET
• Date: February 22
• TV Channel: Fox Sports 1

Bet on Marquette vs. DePaul with FanDuel Sportsbook.

New Mexico vs. Colorado State

• Matchup: No. 22 Colorado State Rams at New Mexico Lobos
• Projected Winner: New Mexico (68.49% win probability)
• Spread: New Mexico (-7.5)
• Time: 10:00 PM ET
• Date: February 22
• TV Channel: CBS Sports Network

Bet on New Mexico vs. Colorado State with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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