Christian McCaffrey Fantasy Football Week 2: Stats and Projections vs. Saints

San Francisco 49ers running back Christian McCaffrey will be up against the team with last year's 31st-ranked rushing defense, the New Orleans Saints (141.4 yards conceded per game), in Week 2 -- kicking off at 1 p.m. ET on Sunday.

Is McCaffrey a DFS option for you this week, as he plays the Saints? More stats and information can be found below, so take a look.

Thinking about playing McCaffrey this week? Start building your FanDuel fantasy football lineup today!

Christian McCaffrey Week 2 Fantasy Football Projection

• Matchup: San Francisco 49ers at New Orleans Saints
• Game Date: September 14, 2025
• Game Time: 1 p.m.
• Projected Fantasy Points: 14.9
• PPR Projected Fantasy Points: 17.2
• Projected Rushing Yards: 71.12
• Projected Rushing TDs: 0.53
• Projected Receiving Yards: 34.41
• Projected Receiving TDs: 0.21

Projections provided by numberFire

McCaffrey 2024 Fantasy Performance

• McCaffrey picked up 32.8 fantasy points (8.2 per game), 69th at his position and 311th in the league.
• In his one game so far this year, McCaffrey had 69 rushing yards on 22 attempts and zero touchdowns, and 73 receiving yards on nine catches (10 targets), ending up with 14.2 fantasy points.
• McCaffrey picked up 10.7 fantasy points -- 13 carries, 39 yards; 6 receptions, 68 yards -- in his best game last year, in Week 10 versus the Tampa Bay Buccaneers.
• In Week 12 against the Green Bay Packers, McCaffrey put up a season-low 4.8 fantasy points, courtesy of this stat line: 11 carries, 31 yards; 3 receptions, 37 yards.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Saints Defensive Performance

• New Orleans surrendered more than 300 passing yards to five QBs last season.
• The Saints gave up at least one passing touchdown to 10 opposing QBs last season.
• In the passing game, New Orleans allowed seven players to throw at least two touchdowns in a game last year.
• In the passing game, the Saints allowed three or more passing touchdowns to only one opposing quarterback last year.
• Through the air, New Orleans gave up more than 100 receiving yards to five players last season.
• Against the Saints last season, 16 players hauled in a TD pass.
• Looking at pass defense, New Orleans allowed just three players to catch at least two touchdown passes against it last year.
• In the run game, six players picked up more than 100 rushing yards in a game against the Saints last season.
• Against New Orleans last season, 16 players rushed for at least one TD.
• In the ground game, the Saints allowed four players to score at least two rushing touchdowns against them last year.

Want more data and analysis on Christian McCaffrey? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.