Christian McCaffrey Fantasy Football Week 12: Stats and Projections vs. Panthers

Christian McCaffrey and the San Francisco 49ers will face the Carolina Panthers and their 16th-ranked rushing defense (113.1 yards conceded per game) in Week 12, on Monday at 8:15 p.m. ET.

For more details on McCaffrey, if you're thinking about him for your DFS roster, check out this article prior to his upcoming game versus the Panthers.

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Christian McCaffrey Week 12 Fantasy Football Projection

• Matchup: San Francisco 49ers vs. Carolina Panthers
• Game Date: November 24, 2025
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 23.6
• PPR Projected Fantasy Points: 27.0
• Projected Rushing Yards: 91.74
• Projected Rushing TDs: 0.78
• Projected Receiving Yards: 68.48
• Projected Receiving TDs: 0.50

Projections provided by numberFire

McCaffrey Fantasy Performance

• McCaffrey has been one of the best players in fantasy at the RB position this season, ranking third with 19.1 fantasy points per game (209.9 total points). He is 10th in fantasy points among all players.
• In his last three games, McCaffrey has put up 69.0 fantasy points (23.0 per game), rushing for 217 yards and scoring three touchdowns on 53 carries. He has also contributed 173 yards on 18 catches (22 targets) with two TDs as a pass-catcher.
• McCaffrey has 107.9 total fantasy points (21.6 per game) in his last five games, carrying the ball 85 times for 371 yards with five touchdowns. In the receiving game, he has added 288 yards on 28 catches (36 targets) with two TDs.
• The highlight of McCaffrey's fantasy season so far was Week 7 against the Atlanta Falcons, when he completed 0.0% of his passes for zero yards and zero touchdowns with interceptions on his way to 32.1 fantasy points. He also had 129 rushing yards on 24 attempts (5.4 YPC) with two touchdowns on the ground.
• From a fantasy standpoint, Christian McCaffrey stumbled to his worst performance of the season in Week 8 against the Houston Texans, rushing eight times for 25 yards, with three receptions for 43 yards as a receiver (6.8 fantasy points).

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Panthers Defensive Performance

• Carolina has not let a player register over 300 yards passing against them in a matchup yet this year.
• The Panthers have given up at least one passing TD to seven opposing QBs this season.
• Carolina has allowed two or more passing TDs to four opposing QBs this year.
• The Panthers have allowed only two players to pass for three or more TDs in a game this year.
• A total of five players have recorded more than 100 yards receiving in a game versus Carolina this year.
• The Panthers have given up a touchdown reception by 13 players this year.
• Carolina has not allowed an opposing player to catch more than one touchdown pass in a game this year.
• Three players have put up over 100 yards rushing in a game against the Panthers this year.
• A total of 10 players have rushed for at least one touchdown versus Carolina this year.
• The Panthers have allowed at least two rushing touchdowns to three players this year.

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