Christian McCaffrey Fantasy Football Week 11: Stats and Projections vs. Cardinals

Christian McCaffrey and the San Francisco 49ers will meet the Arizona Cardinals and their 18th-ranked run defense (114.1 yards conceded per game) in Week 11, on Sunday at 4:05 p.m. ET.

Is McCaffrey a daily fantasy option for you this week, as he goes up against the Cardinals? More stats and information can be found in this article, so take a look.

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Christian McCaffrey Week 11 Fantasy Football Projection

• Matchup: San Francisco 49ers at Arizona Cardinals
• Game Date: November 16, 2025
• Game Time: 4:05 p.m.
• Projected Fantasy Points: 18.5
• PPR Projected Fantasy Points: 21.1
• Projected Rushing Yards: 81.48
• Projected Rushing TDs: 0.59
• Projected Receiving Yards: 49.72
• Projected Receiving TDs: 0.33

Projections provided by numberFire

McCaffrey Fantasy Performance

• McCaffrey has been one of the top players in fantasy at the RB position this season, ranking second with 18.0 fantasy points per game (179.8 total points). He is 11th in fantasy points among all players.
• In his last three games, McCaffrey has picked up 45.7 fantasy points (15.2 per game), rushing for 161 yards and scoring one touchdown on 48 carries. He has also contributed 176 yards on 16 catches (22 targets) with one TD as a receiver.
• McCaffrey has delivered 94.9 total fantasy points (19.0 per game) during his last five games, running the ball 89 times for 344 yards and four scores. In the receiving game, he has tacked on 305 yards on 30 receptions (38 targets) with one TDs.
• The high point of McCaffrey's fantasy season came against the Atlanta Falcons in Week 7, when he piled up 32.1 fantasy points with 129 rushing yards and two TDs on 24 carries. As a receiver, he hauled in seven balls (on eight targets) for 72 yards.
• From a fantasy standpoint, Christian McCaffrey delivered his lowest fantasy-point total of the season (6.8 points) in Week 8 against the Houston Texans, rushing for 25 yards on eight carries with three catches for 43 yards.

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Cardinals Defensive Performance

• Arizona has allowed more than 300 yards passing to only one player this season.
• The Cardinals have allowed seven players to pass for at least one TD in a game this year.
• Arizona has allowed two or more TD passes to two opposing QBs this season.
• Just one player have thrown for at least three touchdowns in a game versus the Cardinals this year.
• Arizona has given up over 100 yards receiving to three players this season.
• The Cardinals have allowed nine players to catch a TD pass against them this year.
• Arizona has given up at least two receiving touchdowns to just one player this season.
• The Cardinals have allowed more than 100 yards on the ground to only one player this season.
• Arizona has allowed eight players to score at least one rushing touchdown against them this year.
• Just one player has rushed for more than one touchdown versus the Cardinals this year.

Want more data and analysis on Christian McCaffrey? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.