Christian McCaffrey Fantasy Football Week 10: Stats and Projections vs. Rams

Christian McCaffrey and the San Francisco 49ers will face the Los Angeles Rams and their 11th-ranked run defense (99.8 yards allowed per game) in Week 10, on Sunday at 4:25 p.m. ET.

Thinking about McCaffrey for your DFS roster, with his next game against the Rams? We've got stats and info for you in this article.

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Christian McCaffrey Week 10 Fantasy Football Projection

• Matchup: San Francisco 49ers vs. Los Angeles Rams
• Game Date: November 9, 2025
• Game Time: 4:25 p.m.
• Projected Fantasy Points: 17.7
• PPR Projected Fantasy Points: 20.3
• Projected Rushing Yards: 78.41
• Projected Rushing TDs: 0.68
• Projected Receiving Yards: 45.47
• Projected Receiving TDs: 0.23

Projections provided by numberFire

McCaffrey Fantasy Performance

• McCaffrey has been one of the top players in fantasy at the RB position this season, ranking second with 18.9 fantasy points per game (170.2 total points). He is ninth in fantasy points among all players.
• Looking at his last three games, McCaffrey has totaled 68.2 fantasy points (22.7 per game) as he's rushed for 260 yards and scored three touchdowns on 60 carries. As a receiver, he's chipped in with 182 yards on 15 grabs (20 targets) with one TDs.
• McCaffrey has generated 105.2 fantasy points (21.0 per game) during his last five games, as he's rushed for 371 yards with four touchdowns on 99 carries. As a receiver, he has chipped in with 321 yards on 30 grabs (37 targets) with two TDs.
• The high point of McCaffrey's season as a fantasy producer came against the Atlanta Falcons in Week 7, as he put up 32.1 fantasy points by catching seven passes (on eight targets) for 72 yards.
• From a fantasy perspective, Christian McCaffrey delivered his lowest fantasy-point total of the year (6.8 points) in Week 8 against the Houston Texans, running for 25 yards on eight carries with three catches for 43 yards.

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Rams Defensive Performance

• One player has recorded over 300 yards passing in a game against Los Angeles this season.
• The Rams have given up at least one passing TD to six opposing QBs this year.
• Los Angeles has allowed two players to pass for at least two TDs in a game this season.
• The Rams have allowed just one player to pass for three or more TDs in a game this season.
• Los Angeles has allowed over 100 yards receiving to three players this year.
• A total of Nine players have hauled in a touchdown pass against the Rams this season.
• No player has hauled in more than one TD pass against Los Angeles this season.
• The Rams have allowed more than 100 yards on the ground to only one player this year.
• A total of two players have rushed for at least one TD versus Los Angeles this year.
• No player has run for more than one TD versus the Rams this season.

Want more data and analysis on Christian McCaffrey? Check out FanDuel Research for all the latest and in-depth fantasy and betting coverage.