Chiefs vs Buccaneers Prediction for NFL Preseason Today - Picks, Odds & Best Bets Saturday

NFL Betting Picks in Summary

• Buccaneers -5.5
• Baker Mayfield 20+ Passing Yards
• Bucky Irving 10+ Rushing Yards

Kansas City and Tampa Bay meet Saturday night, and Baker Mayfield is back under center for the Buccaneers after sitting out last week's game — a real shift in what to expect from this Tampa Bay offense.

All NFL preseason odds come from FanDuel Sportsbook's NFL betting odds and may change after this article is published.

Depth Chart Notes

Tampa Bay: Mayfield has a confirmed passing market this week, along with Bucky Irving at running back and Cyrus Allen at receiver — a real, established group compared to last week's backup-driven look.

Kansas City: Justin Fields continues to fill in for an injured Patrick Mahomes, with a live market of his own again this week.

NFL Predictions and Picks for Preseason Week 2

Kansas City Chiefs at Tampa Bay Buccaneers (Sat, 7:30 p.m. ET)

Buccaneers -5.5 (-110)

Mayfield's return gives Tampa Bay a genuine established starter behind a full group of skill-position players with live markets, a clear edge over a Chiefs offense still working Fields in for an injured Mahomes.

Baker Mayfield 20+ Passing Yards (+132)

Mayfield is a proven full-time NFL starter making his season debut, and a plus-money price on a modest 20-yard floor is fair value for a passer of his caliber.

Bucky Irving 10+ Rushing Yards (+106)

Irving is Tampa Bay's clear starting back behind a confirmed starting quarterback, and a near-even price on a single 10-yard carry looks like a fair number given that setup.