Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 7:12 p.m.

The St. Louis Cardinals are among the MLB teams busy on Saturday, up against the Colorado Rockies.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (71-71) vs. Colorado Rockies (54-87)
• Date: Saturday, September 5, 2026
• Time: 8:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Cardinals.TV

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-130) | COL: (+110)
• Spread: STL: -1.5 (+116) | COL: +1.5 (-140)
• Total: 11.5 -- Over: (+102) | Under: (-124)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Matthew Liberatore (Cardinals) - 5-13, 5.41 ERA vs Mason Adams (Rockies) - 0-0, 3.00 ERA

The Cardinals will give the nod to Matthew Liberatore (5-13, 5.41 ERA), who is eyeing win No. 6 on the season, and the Rockies will counter with Mason Adams. When Liberatore starts, his team is 13-13-0 against the spread this season. Liberatore's team has been victorious in 62.5% of the games he's started as the moneyline favorite with a record of 5-3. Adams has started two games with set spreads, and the Rockies covered in both opportunities. The Rockies were named the moneyline underdog for two Adams starts this season -- they split the games.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (62.8%)

Cardinals vs Rockies Moneyline

• The Cardinals vs Rockies moneyline has St. Louis as a -130 favorite, while Colorado is a +110 underdog at home.

Cardinals vs Rockies Spread

• The Cardinals are at the Rockies and are favored by 1.5 runs on the spread. The Cardinals are +116 to cover the runline, with the Rockies being -140.

Cardinals vs Rockies Over/Under

• Cardinals versus Rockies on Sept. 5 has an over/under of 11.5 runs, with the odds on the over +102 and the under set at -124.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have been victorious in 24, or 55.8%, of the 43 contests they have been chosen as favorites in this season.
• This year St. Louis has won seven of 13 games when listed as at least -130 on the moneyline.
• The Cardinals and their opponents have hit the over in 61 of their 138 games with a total set by oddsmakers this season.
• The Cardinals have an against the spread mark of 75-63-0 in 138 games with a line this season.
• The Rockies have won 51 of the 134 games they were the underdog on the moneyline this season (38.1%).
• In games it has played as a moneyline underdog with odds of +110 or longer, Colorado has a 47-76 record (winning only 38.2% of its games).
• The Rockies have had an over/under set by bookmakers 138 times, and have combined with opponents to go over the total in 65 of those games (65-70-3).
• The Rockies have a 75-63-0 record ATS this season (covering 54.3% of the time).

Cardinals Player Leaders

• Alec Burleson has 33 doubles, a triple, 21 home runs and 48 walks while hitting .281. He has an on-base percentage of .345 and a slugging percentage of .464.
• Among all qualified hitters in the majors, his batting average ranks 21st, his on-base percentage ranks 46th, and he is 37th in slugging.
• Jordan Walker has 156 hits to go with a slugging percentage of .504, both of which lead St. Louis hitters this season. He's batting .289 with an on-base percentage of .343.
• Among qualified batters, his batting average ranks him 12th, his on-base percentage 50th, and his slugging percentage 14th.
• Walker has picked up a hit in four games in a row. During his last five outings he is hitting .318 with three doubles, a home run and three RBIs.
• Ivan Herrera leads St. Louis with an OBP of .359 this season while batting .246 with 69 walks and 86 runs scored.
• Herrera takes a two-game hitting streak into this game. During his last five outings he is hitting .348 with a double, a home run, two walks and six RBIs.
• Nathan Church has 10 home runs, 47 RBI and a batting average of .242 this season.
• Church has safely hit in four straight games. During his last five outings he is hitting .250 with an RBI.

Rockies Player Leaders

• TJ Rumfield has accumulated an on-base percentage of .388 and a slugging percentage of .455. Both lead the Rockies. He's batting .295.
• Including all the qualified hitters in the big leagues, his batting average places him ninth, his on-base percentage is fifth, and he is 43rd in slugging.
• Rumfield hopes to build on a nine-game hitting streak in this matchup. During his last 10 games he is batting .406 with a double, a triple, two home runs, 14 walks and five RBIs.
• Jake McCarthy is batting .289 with 29 doubles, eight triples, 14 home runs and 26 walks. He's slugging .477 with an on-base percentage of .332.
• Including all qualified hitters, his batting average places him 12th, his on-base percentage ranks 69th, and he is 27th in slugging.
• Hunter Goodman has racked up 113 hits, a team-best for the Rockies.
• Willi Castro is batting .260 with 20 doubles, a triple, 15 home runs and 41 walks.

Cardinals vs Rockies Head to Head

• 9/4/2026: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/9/2026: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/8/2026: 8-6 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/7/2026: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +150)
• 8/13/2025: 6-5 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/11/2025: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/23/2025: 6-0 COL (Favorite: Cardinals, Spread: -1.5, Total: 11, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 7/22/2025: 8-4 COL (Favorite: Cardinals, Spread: -1.5, Total: 12, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/21/2025: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/26/2024: 10-8 COL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!