Cardinals vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 20

Odds updated as of 12:12 p.m.

Thursday's slate in the MLB includes a matchup between the St. Louis Cardinals and the Cincinnati Reds.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Cardinals vs Reds Game Info

• St. Louis Cardinals (65-63) vs. Cincinnati Reds (61-66)
• Date: Thursday, August 20, 2026
• Time: 12:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Cardinals.TV

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-108) | CIN: (+100)
• Spread: STL: -1.5 (+136) | CIN: +1.5 (-164)
• Total: 9 -- Over: (-102) | Under: (-120)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Michael McGreevy (Cardinals) - 5-9, 3.48 ERA vs Brady Singer (Reds) - 5-11, 4.66 ERA

The Cardinals will give the nod to Michael McGreevy (5-9, 3.48 ERA), who is eyeing win No. 6 on the season, and the Reds will counter with Brady Singer (5-11, 4.66 ERA). McGreevy's team is 13-11-0 against the spread this season in his starts. McGreevy's team is 3-3 this season when he starts and they are the moneyline favorite. The Reds are 12-11-0 ATS in Singer's 23 starts with a set spread. The Reds are 7-11 in Singer's 18 starts this season that they were the underdog on the moneyline.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (52.6%)

Cardinals vs Reds Moneyline

• The Cardinals vs Reds moneyline has St. Louis as a -108 favorite, while Cincinnati is a +100 underdog at home.

Cardinals vs Reds Spread

• The Cardinals are at the Reds and are favored by 1.5 runs on the spread. The Cardinals are +136 to cover the runline, with the Reds being -164.

Cardinals vs Reds Over/Under

• The over/under for Cardinals-Reds on Aug. 20 is 9. The over is -102, and the under is -120.

Bet on St. Louis Cardinals vs. Cincinnati Reds on FanDuel today!

Cardinals vs Reds Betting Trends

• The Cardinals have won in 22, or 56.4%, of the 39 contests they have been named as odds-on favorites in this year.
• This year St. Louis has won 22 of 40 games when listed as at least -108 on the moneyline.
• The Cardinals and their opponents have gone over in 50 of their 124 games with a total set by sportsbooks this season.
• The Cardinals have posted a record of 67-57-0 against the spread this season.
• The Reds have put together a 39-43 record in games they were listed as the moneyline underdog (winning 47.6% of those games).
• In games it has played as a moneyline underdog with odds of +100 or longer, Cincinnati has a 28-40 record (winning 41.2% of its games).
• In the 124 games bookmakers have set an over/under for the Reds, they have combined with opponents to go over the total 65 times (65-57-2).
• The Reds have a 65-59-0 record against the spread this season (covering 52.4% of the time).

Cardinals Player Leaders

• Alec Burleson leads St. Louis with a slugging percentage of .491, fueled by 55 extra-base hits. He has a .289 batting average and an on-base percentage of .354.
• Among qualifying batters in baseball, his batting average ranks 15th, his on-base percentage ranks 39th, and he is 21st in slugging.
• Burleson has picked up at least one hit in six games in a row. In his last 10 games he is hitting .359 with five doubles, two home runs, three walks and 14 RBIs.
• Jordan Walker has 139 hits, which leads St. Louis batters this season. He's batting .288 with 53 extra-base hits. He's also slugging .502 with an on-base percentage of .347.
• Among qualified batters, his batting average ranks him 16th, his on-base percentage 51st, and his slugging percentage 15th.
• Walker has picked up a hit in five straight games. In his last five games he is hitting .476 with four doubles, two home runs, a walk and six RBIs.
• JJ Wetherholt has collected 115 base hits, an OBP of .348 and a slugging percentage of .374 this season.
• Ivan Herrera leads St. Louis in OBP (.359) this season, fueled by 116 hits.

Reds Player Leaders

• Sal Stewart has put up a slugging percentage of .476 and has 125 hits, both team-best numbers for the Reds. He's batting .259 and with an on-base percentage of .334.
• Including all the qualified hitters in the big leagues, his batting average ranks 65th, his on-base percentage ranks 69th, and he is 31st in slugging.
• Stewart hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .211 with a double, a home run, a walk and three RBIs.
• Elly De La Cruz leads his team with a .340 OBP. He has a batting average of .259 while slugging .468.
• Including all qualified players, he is 65th in batting average, 59th in on-base percentage and 37th in slugging percentage.
• JJ Bleday has 13 doubles, a triple, 20 home runs and 57 walks while batting .218.
• Tyler Stephenson is hitting .242 with 16 doubles, 12 home runs and 37 walks.

Cardinals vs Reds Head to Head

• 8/19/2026: 5-4 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +126)
• 8/18/2026: 3-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: +104)
• 8/17/2026: 6-5 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: +108)
• 8/17/2026: 2-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 7/26/2026: 5-3 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/25/2026: 7-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/24/2026: 4-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/7/2026: 5-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/6/2026: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/5/2026: 10-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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