BYU vs Iowa State Prediction, Odds, Picks, Best Bets for Week 6 2026

NCAA football action on Friday includes the BYU Cougars playing the Iowa State Cyclones.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

BYU vs Iowa State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BYU: (-400) | Iowa State: (+310)
• Spread: BYU: -10.5 (-102) | Iowa State: +10.5 (-120)
• Total: 46.5 -- Over: (-112) | Under: (-108)

BYU vs Iowa State Betting Trends

• BYU hasn't lost a game against the spread this year.
• BYU is unbeaten ATS (2-0) as a 10.5-point favorite or greater this season.
• Two of BYU's four games have gone over the point total.
• Iowa State has beaten the spread three times in five games.
• Iowa State is unbeaten ATS (1-0) as a 10.5-point underdog or more this year.
• There have been three Iowa State games (out of five) that went over the total this year.

BYU vs Iowa State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (73.4%)

BYU vs Iowa State Point Spread

BYU is favored by 10.5 points (-102 to cover) in this matchup. Iowa State, the underdog, is -120.

BYU vs Iowa State Over/Under

The over/under for BYU-Iowa State on Oct. 9 is 46.5. The over is -112, and the under is -108.

BYU vs Iowa State Moneyline

Iowa State is a +310 underdog on the moneyline, while BYU is a -400 favorite.

BYU vs. Iowa State Points Insights

BYU vs. Iowa State Game Info

• Game day: Friday, October 9, 2026
• Game time: 10:15 p.m. ET
• TV channel: ESPN
• Location: Provo, Utah
• Stadium: LaVell Edwards Stadium

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Check out even more in-depth BYU vs. Iowa State analysis on FanDuel Research.