Braves vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 22

Odds updated as of 7:11 p.m.

MLB action on Tuesday includes the Atlanta Braves taking on the Cincinnati Reds.

We've got you covered, in terms of the most important information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Braves vs Reds Game Info

• Atlanta Braves (92-64) vs. Cincinnati Reds (72-84)
• Date: Tuesday, September 22, 2026
• Time: 7:15 p.m. ET
• Venue: Truist Park -- Atlanta, Georgia
• Coverage: BravesVsn and Reds.TV

Braves vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ATL: (-230) | CIN: (+190)
• Spread: ATL: -1.5 (-108) | CIN: +1.5 (-111)
• Total: 9.5 -- Over: (+106) | Under: (-130)

Braves vs Reds Probable Starting Pitchers

Probable Pitchers: JR Ritchie (Braves) - 1-3, 5.03 ERA vs Brandon Williamson (Reds) - 4-4, 5.56 ERA

The probable pitchers are JR Ritchie (1-3) for the Braves and Brandon Williamson (4-4) for the Reds. Ritchie and his team have a record of 5-4-0 against the spread when he starts. Ritchie's team is 2-2 this season when he starts and they are the moneyline favorite. The Reds have gone 4-3-0 against the spread when Williamson starts. The Reds are 3-2 in Williamson's five starts this season that they were the underdog on the moneyline.

Braves vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Braves win (66.9%)

Braves vs Reds Moneyline

• Cincinnati is the underdog, +190 on the moneyline, while Atlanta is a -230 favorite at home.

Braves vs Reds Spread

• The Reds are +1.5 on the run line against the Braves. The Reds are -111 to cover, and the Braves are -108.

Braves vs Reds Over/Under

• A combined run total of 9.5 has been set for Braves-Reds on Sept. 22, with the over at +106 and the under at -130.

Bet on Atlanta Braves vs. Cincinnati Reds on FanDuel today!

Braves vs Reds Betting Trends

• The Braves have been chosen as favorites in 105 games this year and have walked away with the win 67 times (63.8%) in those games.
• Atlanta has a record of 4-1 when favored by -230 or more this year.
• Contests with the Braves have gone over the total set by oddsmakers in 70 of 150 chances this season.
• The Braves have an against the spread record of 80-70-0 in 150 games with a line this season.
• The Reds are 50-58 in games they were the underdog on the moneyline (winning 46.3% of those games).
• Cincinnati has played four times as a moneyline underdog with odds of +190 or longer, and lost each game.
• The Reds have played in 152 games with a set over/under, and have combined with their opponents to go over the total 81 times (81-69-2).
• The Reds are 77-75-0 against the spread this season.

Braves Player Leaders

• Matt Olson leads Atlanta with 153 hits, batting .253 this season with 73 extra-base hits. He has an on-base percentage of .324 and a slugging percentage of .506.
• He is 74th in batting average, 79th in on-base percentage, and 14th in slugging among all qualifying hitters in the majors.
• Michael Harris II has hit 26 homers this season while driving in 85 runs. He's batting .289 this season and slugging .486 with an on-base percentage of .318.
• He ranks 12th in batting average, 91st in on-base percentage and 21st in slugging in MLB.
• Ozzie Albies is batting .242 with a .402 slugging percentage and 72 RBI this year.
• Drake Baldwin leads Atlanta with an OBP of .356 this season while batting .282 with 54 walks and 83 runs scored.
• Baldwin has hit safely in three straight games. During his last five outings he is hitting .364 with two doubles, a home run, two walks and two RBIs.

Reds Player Leaders

• Sal Stewart has a .470 slugging percentage, which paces the Reds. He's batting .268 with an on-base percentage of .334.
• Including all the qualified hitters in the big leagues, his batting average ranks 44th, his on-base percentage ranks 63rd, and he is 30th in slugging.
• Elly De La Cruz paces his team with 153 hits and a .366 OBP. He has a batting average of .285 while slugging .515.
• Including all qualifying hitters, his batting average places him 14th, his on-base percentage is 19th, and he is 10th in slugging.
• JJ Bleday is batting .215 with 16 doubles, two triples, 23 home runs and 71 walks.
• Eugenio Suarez is batting .209 with 17 doubles, 24 home runs and 52 walks.

Braves vs Reds Head to Head

• 5/31/2026: 6-4 CIN (Favorite: Braves, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/30/2026: 5-2 ATL (Favorite: Braves, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/29/2026: 8-3 ATL (Favorite: Braves, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/1/2025: 3-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/31/2025: 12-11 ATL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/8/2025: 5-4 ATL (Favorite: Braves, Spread: -1.5, Total: 8, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/7/2025: 4-3 CIN (Favorite: Braves, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/6/2025: 2-1 ATL (Favorite: Braves, Spread: -1.5, Total: 8, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/5/2025: 4-0 ATL (Favorite: Braves, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/19/2024: 15-3 ATL (Favorite: Braves, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!