Bills vs Chargers Prediction, Odds, Picks, Best Bets for NFL Week 3

The NFL's Sunday slate includes the Buffalo Bills taking on the Los Angeles Chargers.

We've got you covered, in terms of the most important info about NFL betting lines, before you make your wager on FanDuel Sportsbook.

Bills vs Chargers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (77.3%)

Bills vs Chargers Point Spread

The Bills are 7.5-point favorites against the Chargers. The Bills are +100 to cover the spread, while the Chargers are -122 to cover as a 7.5-point underdog.

Bills vs Chargers Over/Under

The over/under for the Bills versus Chargers matchup on Sept. 27 has been set at 50.5, with -105 odds on the over and -115 odds on the under.

Bills vs Chargers Moneyline

Buffalo is the favorite, -375 on the moneyline, while Los Angeles is a +300 underdog on the road.

Bills vs Chargers Betting Trends

• Buffalo has won twice against the spread this season.
• Every Bills game has hit the over this year.
• The Chargers have no wins against the spread this season.
• No Chargers game has gone over the point total this year.

Check out even more in-depth Bills vs. Chargers analysis on FanDuel Research.

Bills vs Chargers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BUF: (-375) | LAC: (+300)
• Spread: BUF: -7.5 (100) | LAC: +7.5 (-122)
• Total: 50.5 -- Over: (-105) | Under: (-115)

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