Bills vs Chargers Prediction, Odds, Picks, Best Bets for NFL Week 3

The NFL slate on Sunday includes the Buffalo Bills taking on the Los Angeles Chargers.
All the info you need is below, in order to make a smart wager on this game at FanDuel Sportsbook.
Bills vs Chargers Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (77.3%)
Bills vs Chargers Point Spread
The Bills are 7-point favorites against the Chargers. The Bills are -115 to cover the spread, while the Chargers are -105 to cover as a 7-point underdog.
Bills vs Chargers Over/Under
A total of 50.5 points has been set for the Bills-Chargers game on Sept. 27, with the over available at -105 and the under at -115.
Bills vs Chargers Moneyline
The Bills vs Chargers moneyline has Buffalo as a -375 favorite, while Los Angeles is a +300 underdog on the road.
Bills vs Chargers Betting Trends
- Buffalo has won twice against the spread this year.
- Two Bills games (out of two) have gone over the point total this year.
- The Chargers have no wins against the spread this year.
- The Chargers and their opponent have yet to hit the over this year.
Check out even more in-depth Bills vs. Chargers analysis on FanDuel Research.
Bills vs Chargers Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: BUF: (-375) | LAC: (+300)
- Spread: BUF: -7 (-115) | LAC: +7 (-105)
- Total: 50.5 -- Over: (-105) | Under: (-115)
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