Amon-Ra St. Brown Fantasy Football Week 2: Stats and Projections vs. Bills

Detroit Lions wide receiver Amon-Ra St. Brown will take on the team with last season's top-ranked passing defense, the Buffalo Bills (156.9 yards allowed per game), in Week 2 -- kicking off at 8:15 p.m. ET on Thursday.

For more info on St. Brown, if you're considering him for your DFS lineup, read this piece before his upcoming matchup versus the Bills.

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Amon-Ra St. Brown Week 2 Fantasy Football Projection

• Matchup: Detroit Lions at Buffalo Bills
• Game Date: September 17, 2026
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 12.5
• PPR Projected Fantasy Points: 16.4
• Projected Receiving Yards: 88.37
• Projected Receiving TDs: 0.57

Projections provided by numberFire

St. Brown 2025 Fantasy Performance

• St. Brown was near the league lead -- third at his position, 35th overall -- with 207.0 fantasy points (12.2 per game).
• In his one game this year, St. Brown accumulated 18.7 fantasy points. He had 67 receiving yards on 10 catches (14 targets) and two touchdowns.
• In his best performance last season -- Week 2 versus the Chicago Bears -- St. Brown accumulated 30.2 fantasy points. His stat line: nine catches, 115 yards and three touchdowns.
• In Week 15 against the Los Angeles Rams, St. Brown posted 28.4 fantasy points (his second-highest total last season), with this stat line: 13 receptions, 164 yards and two touchdowns.
• St. Brown recorded 4.2 fantasy points -- two catches, 42 yards, on 12 targets -- in Week 11 against the Philadelphia Eagles, and that was his second-worst performance of the year.

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Bills Defensive Performance

• In last year's action, Buffalo did not allow a quarterback to post more than 300 passing yards in a game.
• The Bills surrendered at least one passing touchdown to 12 opposing QBs last season.
• Against Buffalo last season, five players threw for at least two touchdowns in a game.
• Versus the Bills last year, just one player threw for at least three touchdowns in a game.
• Through the air, Buffalo gave up over 100 receiving yards to only three players last season.
• In terms of pass defense, the Bills gave up a touchdown reception to 18 players last season.
• Looking at pass defense, Buffalo allowed just one player to catch at least two touchdown passes against it last year.
• In the ground game, five players collected more than 100 rushing yards in a game against the Bills last season.
• In terms of run defense, Buffalo allowed at least one rushing touchdown to 18 players last season.
• The Bills allowed at least two rushing TDs on the ground to six players last year.

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