49ers vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 3

Sunday's slate in the NFL includes a matchup between the San Francisco 49ers and the Arizona Cardinals.

All the info you need is below, in order to make a smart wager on this matchup at FanDuel Sportsbook.

49ers vs Cardinals Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction:

49ers vs Cardinals Point Spread

The 49ers are 7.5-point favorites against the Cardinals. The 49ers are -106 to cover the spread, while the Cardinals are -114 to cover as a 7.5-point underdog.

49ers vs Cardinals Over/Under

A total of 48.5 points has been set for the 49ers-Cardinals matchup on Sept. 27, with the over available at -105 and the under at -115.

49ers vs Cardinals Moneyline

Arizona is the underdog, +315 on the moneyline, while San Francisco is a -400 favorite at home.

49ers vs Cardinals Betting Trends

• San Francisco has two wins against the spread this year.
• The 49ers are unbeaten ATS (1-0) as a 7.5-point favorite or greater this year.
• The 49ers have had one game (out of two) hit the over this season.
• The Cardinals have won once against the spread this year.
• Arizona has covered every time (1-0) as a 7.5-point or greater underdog this year.
• The Cardinals and their opponent have yet to go over the total this year.

Check out even more in-depth 49ers vs. Cardinals analysis on FanDuel Research.

49ers vs Cardinals Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-400) | ARI: (+315)
• Spread: SF: -7.5 (-106) | ARI: +7.5 (-114)
• Total: 48.5 -- Over: (-105) | Under: (-115)

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