49ers vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 3

The NFL slate on Sunday includes the San Francisco 49ers facing the Arizona Cardinals.

We've got you covered, in terms of the vital information about NFL betting lines, before you make your wager on FanDuel Sportsbook.

49ers vs Cardinals Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (80.7%)

49ers vs Cardinals Point Spread

The 49ers are 8.5-point favorites against the Cardinals. The 49ers are -110 to cover the spread, while the Cardinals are -110 to cover as an 8.5-point underdog.

49ers vs Cardinals Over/Under

A total of 47.5 points has been set for the 49ers-Cardinals game on Sept. 27, with the over available at -115 and the under at -105.

49ers vs Cardinals Moneyline

Looking at the moneyline for 49ers-Cardinals, San Francisco is the favorite at -461, and Arizona is +360 playing on the road.

49ers vs Cardinals Betting Trends

• San Francisco has covered the spread in every game this season.
• The 49ers have covered every time (1-0) as an 8.5-point favorite or greater this season.
• The 49ers have had one game (out of two) go over the total this year.
• The Cardinals have one win against the spread this year.
• Arizona has covered every time (1-0) as an 8.5-point or greater underdog this year.
• No Cardinals game has gone over the point total this year.

Check out even more in-depth 49ers vs. Cardinals analysis on FanDuel Research.

49ers vs Cardinals Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-461) | ARI: (+360)
• Spread: SF: -8.5 (-110) | ARI: +8.5 (-110)
• Total: 47.5 -- Over: (-115) | Under: (-105)

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