Buffalo vs Miami (OH) Prediction, Odds, Picks, Best Bets for Week 13 2025

The Miami (OH) RedHawks versus the Buffalo Bulls is on the college football schedule for Wednesday.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

Miami (OH) vs Buffalo Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Miami (OH): (-126) | Buffalo: (+108)
• Spread: Miami (OH): -2.5 (-110) | Buffalo: +2.5 (-110)
• Total: 38.5 -- Over: (-110) | Under: (-110)

Miami (OH) vs Buffalo Betting Trends

• Miami (OH) has beaten the spread six times in 10 games.
• Miami (OH) has yet to lose ATS (5-0) as a 2.5-point favorite or greater this season.
• Miami (OH) has played 10 games this year, and five of them have gone over the total.
• Buffalo has four wins in 10 contests against the spread this year.
• As a 2.5-point underdog or more, Buffalo has two wins ATS (2-1).
• Of 10 Buffalo games so far this season, five have hit the over.

Miami (OH) vs Buffalo Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: RedHawks win (68.5%)

Miami (OH) vs Buffalo Point Spread

Buffalo is the underdog by 2.5 points against Miami (OH). Buffalo is -110 to cover the spread, and Miami (OH) is -110.

Miami (OH) vs Buffalo Over/Under

Miami (OH) versus Buffalo on Nov. 19 has an over/under of 38.5 points, with the over -110 and the under -110.

Miami (OH) vs Buffalo Moneyline

Miami (OH) is the favorite, -126 on the moneyline, while Buffalo is a +108 underdog.

Miami (OH) vs. Buffalo Points Insights

Miami (OH) vs. Buffalo Game Info

• Game day: Wednesday, November 19, 2025
• Game time: 7 p.m. ET
• TV channel: ESPN2
• Location: Buffalo, New York
• Stadium: UB Stadium

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Check out even more in-depth Miami (OH) vs. Buffalo analysis on FanDuel Research.